Friday, May 8, 2015
Using real-time MRI, Dr. Keith Horvath's group at the NIH's National Heart, Lung, and Blood Institute (NHLBI) can precisely implant a replacement porcine heart valve using a collapsible stent more safely and quickly than with standard techniques.
"The reason for using [real-time] MRI is three-fold," Dr. Horvath explains...
Wednesday, May 6, 2015
Have you ever wondered why someone becomes a biochemist or a biophysicist, or how to find a career in both fields at the same time? Peter Bandettini, Ph.D., is Director of the Functional Magnetic Resonance Facility and Chief of the Unit on Functional Imaging Methods at the National Institute of Mental Health (NIMH). In the interview below, he shares some thoughts on what motivates him and what it's like working at the NIH IRP.
Monday, May 4, 2015
When I was growing up, my grandfather would visit and try to teach me thermodynamics. At the time, I thought that this was normal conversation between a grandfather and a little girl. It was several years before I realized that he was an eminent scientist in his home country. My grandfather would always ask me, “How is your science?”
Friday, May 1, 2015
This dapper bee from 1977 advertised an NHLBI-sponsored multicenter, randomized, double-blind, and placebo-controlled trial designed to test the benefits of beta-blockers for people who had had a heart attack. The study was called the Beta-Blocker Heart Attack Trial (BHAT). Ah, you say—that’s why the bee in the hat!
Wednesday, April 29, 2015
Following on the successful launch and continued expansion of the IRP Web site, we turned our attention to developing a new, allied Web site to give people a broader view of the programs overseen by the Office of Intramural Research (OIR). The new site (oir.nih.gov), which is officially making its debut today, is intended to provide “one-stop shopping” regarding the oversight and coordination of the research, training, and technology transfer activities that take place within each Institute’s and Center’s intramural program, across all of our research campuses nationwide.
Monday, April 27, 2015
One of the best parts of a new idea is being able to share it! Research is certainly no exception. On Thursday, April 30th, the postbacs of NIH will be sharing their ideas and findings at Postbac Poster Day.
Thursday, April 23, 2015
We honor Dr. Hans L. Falk (1919 -1985) this Earth Day (April 22, but celebrated today, April 23, at NIH) for his significant contributions to the field of environmental health science as both a scientist and an administrator.
Monday, April 20, 2015
Ever since the discovery of the double-helix structure of DNA, scientists have sought ways to edit the genome. Altering gene expression partially and transiently via small interfering RNA has come a long way, and the progress has been spectacular. However, achieving complete and sustained modification of gene expression in a cell remains a tedious procedure that is often costly and time-consuming. For molecular biologists working with cell lines, quick and efficient knock out of one or more genes would provide a powerful tool for their studies. The CRISPR technology arrived two years ago to potentially fulfill that need.
Friday, April 17, 2015
Countries that grow poppies used to hold a monopoly on the ingredients to the main opiate painkilling drugs. Then in 1979, Dr. Kenner Rice of NIDDK’s Laboratory of Medicinal Chemistry (he is now at NIDA) discovered the critical chemical reaction enabling large-scale production of totally synthetic morphine, codeine, and thebaine, the three basic raw materials in opium.
Wednesday, April 15, 2015
Welcome to LabTV! If you haven’t already, take a look at this video. I hope you will enjoy meeting the first young scientist featured in this brand new series that I’ve chosen to highlight on my blog. The inspiration for LabTV comes from Jay Walker, who is the founder of PriceLine, and curator and chairman of TEDMED, an annual conference focused on new ideas in health and medicine.