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I am Intramural Blog

I am Intramural Blog

Three-Minute Talks: A Succinct Showcase of Science

Annual Competition Tests Researchers’ Communication Skills

Wednesday, July 23, 2025

alarm clock

Everyone recognizes that science can’t just stay in the lab — it can only do good if it finds applications out in the wider world, whether that’s in the form of new technologies, new medical treatments, or a change in public policy. However, the importance of getting scientists out of the lab to engage with the public has been emphasized much less until recently. One of NIH’s approaches to solving that problem is its annual Three-Minute Talks (TmT) competition, which encourages NIH postbaccalaureate fellows, graduate students, and postdoctoral fellows to figure out a way to succinctly explain their research to people who may know nothing at all about what they do.

The (Future) Doctor Is In

Medical Students Enjoy a Year at NIH

Wednesday, July 16, 2025

NIH MRSP participant Quashawn Chadwick

Every physician spends years in school getting trained to provide healthcare to patients with a wide array of health conditions, but not all of them know much about how the tools they use and the treatments they offer make it from the lab to the clinic. For the past year, 42 medical students took time off from their studies to fill in that gap first-hand by working in IRP labs as part of NIH’s Medical Research Scholars Program. As their stints at NIH wind down, each of them will return to medical school with valuable scientific training that will surely enhance their ability to help patients in the future. Keep reading to see how the MRSP has given a leg up to three of these bright future doctors.

A Brain Signal Biomarker for Cerebral Palsy Treatments

Study Points to Potential Way to Improve Physical Therapy Interventions for Movement Disorder

Wednesday, July 9, 2025

boy with cerebral palsy receiving physical therapy

It’s easy to take everyday activities like walking and typing for granted, but for people with cerebral palsy, any movement can be a struggle. Intensive physical therapy, starting at a young age, has long helped those individuals move more easily. Now, recent IRP research could provide a way to track how those and other treatments affect communication within the brain during movement, providing a tool that could help researchers more quickly evaluate which treatments work and which don’t.

Alcohol Accelerates Cardiovascular Aging

IRP Research Suggests Older Adults May Benefit From Severely Limiting Alcohol Consumption

Tuesday, June 24, 2025

illustration of heart and lungs overlaid over an older woman

It seems like every news report touting the health benefits of a daily glass of wine is soon followed by another that claims consuming any amount of alcohol harms health. While the jury is still out on this issue for younger individuals, a recent IRP study suggests that alcohol consumption may accelerate the typical age-related erosion of the cardiovascular system.

Many scientific studies have established the myriad ways that aging and alcohol independently diminish the capacity of the heart and blood vessels to effectively move blood — and the vital oxygen and nutrients it carries — around the body. However, the effects of those two forces in combination remains an outstanding question with potentially significant implications for health and public policy.

Here Come the Computers

NIH AI Symposium Highlights IRP Efforts to Harness Artificial Intelligence

Wednesday, June 11, 2025

human body covered with computer code

Artificial intelligence is permeating seemingly every aspect of society — it’s even the villain in the latest Mission Impossible movie. Biomedical research is no exception to this trend, as showcased at this year’s NIH AI Symposium. The day-long event on May 16 showcased the many ways IRP researchers are harnessing the ever-growing learning capabilities of computers to explore how our bodies work and improve our health.

In between fascinating lectures by IRP senior investigators and visiting scholars from Harvard Medical School and the Massachusetts Institute of Technology, a handful of IRP postbaccalaureate fellows, graduate students, and postdocs also gave short talks about how their labs are utilizing AI and machine learning in their research. Read on to learn about how four of these efforts could one day help speed up therapeutic development for cancer and rare diseases, reveal the relationship between brain activity and behavior, and identify patients with sickle cell disease who would benefit the most from high-risk, intensive treatments.

A Crystal Ball for Prostate Cancer Treatment

IRP’s Dr. Adam Sowalsky Looks to Tumors’ Origins to Predict Outcomes

Wednesday, June 4, 2025

crystal ball

"Skate to where the puck is going, not where it has been." — hockey great Wayne Gretzky

Imagine two men, both diagnosed with prostate cancer. For one, the disease will remain a quiet shadow, never seriously threatening his life. For the other, it will become an aggressive adversary, resisting treatments and altering his future. This June, as Men's Health Month brings such realities into focus, a critical question echoes in clinics and labs: how can we identify early on which cancer will turn dangerous, and how can we use that knowledge to change a patient's outcome for the better? 

IRP senior investigator Adam G. Sowalsky, Ph.D., believes the answer lies not just in how cancer adapts during treatment, but in the evolutionary traits it already possesses when it first emerges. 

A Peek at This Year’s Postbac Poster Day

Annual Event Provides Showcase for IRP Postbaccalaureate Fellows

Wednesday, May 28, 2025

IRP postbac fellow Angel Obiorah with her research poster

As informative as undergraduate science courses can be, there’s no better way to learn the ins and outs of biology than to scrutinize and manipulate it in the lab every day. That’s why so many science enthusiasts flock to NIH after college to participate in the IRP Postbaccalaureate IRTA Program, which allows newly minted grads to spend a year or two working full-time in a lab at NIH. And rather than demonstrating the knowledge they’ve gained on a test, IRP postbacs get to present their research at NIH’s Postbac Poster Day each year, an environment akin to the poster sessions at scientific conferences many postbacs will be attending as they continue their scientific careers.

This year, more than 900 IRP postbacs showed off their research at the event, and unlike prior years, all their presentations were done during one absolutely jam-packed day rather than being spread over two days. Read on to learn about how five of them have taken advantage of the opportunity to work in IRP labs over the past year.

Calming Kids’ Runaway Emotions

Brain Research Helps Understand and Treat Childhood Anxiety

Monday, May 19, 2025

young girl with glowing brain

It’s perfectly normal for young children to throw tantrums or be nervous on their first day of school, and for adolescents to be anxious about what their peers think of them. However, for some children and teens, negative emotions can escalate to unhealthy levels, resulting in significant distress and impairing their quality of life. 

IRP senior investigator Daniel Pine, M.D., is on a mission to understand how that happens and figure out ways to help those kids. In honor of Mental Health Month, we talked with Dr. Pine about how his research is revolutionizing the field of pediatric psychiatry and paving the way for new, non-pharmaceutical treatments.

Dieting May Disrupt Women’s Sleep

IRP Study Reveals Influence of Calorie Intake and Reproductive Cycle on Sleep

Tuesday, May 13, 2025

woman yawning at work

Doctors have long emphasized the importance of maintaining a healthy body weight and getting enough sleep, but in our time-limited lives, we often have to choose between spending time exercising, preparing healthy meals, and getting sufficient shuteye. And the number of hours in the day may not be the only thing that pits weight loss against sleep. A recent IRP study suggests that young women who are not obese get poorer sleep when they change their diets in order to lose weight.

Startling Snapshots of Science

Vibrant Images Push Forward Environmental Health Research

Monday, May 5, 2025

cell junctions in tracheal epithelial cells from a TLR5 knockout mouse

Scientists and artists obviously don’t spend their days doing the same thing, but that doesn’t mean the former can’t sometimes inadvertently be the latter. Take for example the 14 IRP research fellows who submitted images to the most recent edition of the Fellows Scientific Image Competition at NIH’s National Institute of Environmental Health Sciences (NIEHS). The competition, held every few years, shows that biomedical science can not only save lives, but also look good doing it.

“We are excited to showcase the work of our trainees using visual media, which reminds us there is art in science and showcases the important research we’re all engaged in at NIEHS,” says NIEHS Scientific Director Darryl Zeldin, M.D., who initiated the competition.

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This page was last updated on Friday, January 14, 2022

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