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Conditions and Diseases

Cancers

Novel immunotherapy approach treats rare cancer-causing condition 2023
A personalized clinical decision tool for women at high-risk of breast cancer 2022
Frequent use of chemical hair straighteners and relaxers is associated with uterine cancer 2022
Targeted therapy improves survival for younger lymphoma patients 2022
A new treatment for kidney cancers related to von Hippel-Lindau disease 2021
Diabetes drug may lower risk of certain types of breast cancer 2021
Genetically engineering immune cells to stop cancer from spreading 2021
How the cell’s DNA replication machinery overcomes obstacles 2021
Modeling the interplay between processes that induce cancer-causing mutations 2021
A less toxic frontline therapy for adults with Burkitt lymphoma 2020
A novel method for producing astatine-based cancer therapeutics 2020
Blood test predicts liver cancer risk 2020
Changing fate by personalizing treatment for a high-risk blood cancer 2020
Discovery of a new form of immunotherapy for the treatment of cancer 2020
First therapy approved for children with genetic tumor syndrome 2020
Treating a rare HIV-associated cancer without chemotherapy 2020
A simple way to screen for cervical cancer with a smartphone 2019
Cellular diversity helps liver cancer shrug off immunotherapy 2019
Drugs for DIPG: a guide for new therapies in a rare, lethal pediatric brain cancer 2019
Revealing the structure of a sugar-transferring enzyme associated with colorectal cancer 2019
Stress hormones regulate stomach inflammation 2019
Bugs or bacon? How diet and the microbiome influence colorectal cancer risk 2018
Controlling liver cancer via the gut microbiome 2018
Metarrestin: a new approach to targeting the leading cause of cancer mortality 2018
Discovering how cells repair lethal DNA-protein crosslinks 2017
Fostering the first FDA-approved drug for Merkel cell carcinoma 2017
FOUND: essential genes for cancer immunotherapy 2017
How tumors invade and destroy tissues 2017
Mapping platinum in the inner ear after chemotherapy 2017
New biomarkers associated with lingering cancer treatment fatigue symptoms 2017
Engineering immunity to tumor elements 2016
Enhanced risk-based lung cancer screening may prevent more deaths 2016
Stimulating interferon genes to interfere with cancer 2016
Harnessing the immune system to fight epithelial cancers 2015
HPV test better predicts cervical cancer risk than Pap test 2014
Time between morning wake-up and smoking a cigarette associated with rate of lung cancer risk 2014
Deciphering how chromosomal mix-ups lead to tumors 2010
Foundation for CAR T-cell therapy Yescarta 2010
The HPV vaccine: Two decades of research pays off 2001
There’s no “magic bullet” for cancer. Or is there? 2001
Finding one disease is actually many: Diffuse large B-cell lymphomas 2000
Understanding and sensing DNA damage 1998
Lifting the lid on kidney cancer: Exposing the underlying genetics 1995
Discovering a growth factor and its incredible healing powers 1989

Genetics and Birth Defects

Genetic mutation associated with a form of muscular dystrophy can also block nose development 2023
Identification of a new genetic disorder affecting the brain and skull 2021
Age and ancestry affect production of induced pluripotent stems cells 2020
Visualizing the structure and coordination of the DNA replication machinery 2019
A novel mRNA modification may impact the human genetic code 2018
Control of secretory granule maturation by the pgant9 gene 2018
Iron exporter mutations provide malaria protection but predispose African Americans to iron overload disease 2018
Is cigarette choice genetic? Examining connections between race and a preference for menthol 2018
Mitochondria in age-related disease: the importance of heteroplasmy 2018
Promising new treatment for fatal neurological disease Niemann-Pick type C1 2018
Discovering X-linked acrogigantism: a new infant-onset overgrowth syndrome 2017
Extending the genetic code: identifying new DNA bases 2016
Gene therapy to restore the architecture of the inner ear 2016
Linking genetics to recurrent strokes in children with DADA2 2014
Studying childhood stroke to better understand inflammatory diseases 2014
They might be giants: Understanding a childhood genetic defect 2014
Power in numbers: identifying new genes associated with ankylosing spondylitis 2013
Tackling the mysteries of osteosarcoma in children by uncovering gene variants associated with risk 2013
A new approach to treating organ damage in inflammatory diseases 2012
DNA and damage control: A complex web of players 2012
Using genetics to understand stuttering 2012
Team science unravels the link between ALS and FTD 2011
Breaking down complex autoinflammatory diseases, and building up new hope 1997
Therapy for inherited enzyme deficiencies 1991

Infections

A single-shot Marburg vaccine shows promise 2023
Low-dose monoclonal antibody injections prevent malaria infection 2023
New technology provides hope for HIV cure strategies 2023
Thwarting the flu with nanoparticle-based universal influenza vaccines 2022
Biological activity-based modeling identifies potential COVID-19 treatments 2021
Using monoclonal antibodies to prevent malaria 2021
A Nobel win for the discovery of the hepatitis C virus 2020
Coronavirus’ cellular exit strategy may aid its spread through the body 2020
Developing a crucial animal model for studying COVID-19 2020
Genetic and immunologic underpinnings of some cases of severe COVID-19 2020
How the malaria parasite feeds inside a red blood cell 2020
Rapid development of safe and effective COVID-19 vaccines 2020
Assessing vital therapies for Ebola in the midst of an outbreak 2019
Trust your gut: probiotics could directly block staphylococcus infection 2018
Three-in-one antibody protects monkeys from HIV-like virus 2017
Identifying novel monoclonal antibodies against Ebola virus 2016
Repurposed drugs to the rescue: treating Zika 2016
Repurposing existing drugs and discovering new antivirals for hepatitis C 2015
Repurposing drugs to fight Ebola 2014
Revealing drug-resistant malaria’s genetic and molecular fingerprint 2014
Simple new tool makes treatment for neglected tropical diseases safer 2014
Testing a potential vaccine for the Chikungunya virus 2014
Can fewer doses of HPV vaccine provide immunity? 2013
Candidate vaccine against RSV, a common childhood infection 2013
Developing a vaccine for all four dengue viruses 2013
Discovering a new hepatitis C gene—and its implications for precision medicine 2013
Investigational malaria vaccine found to be safe and protective 2013
Seeing the shape of hepatitis B’s action 2013
Can we outwit the influenza virus with a universal vaccine? 2012
Identifying a promising HIV vaccine target 2012
Visualizing a viral infection as it happens 2012
Understanding bacterial immune systems 2011
Illuminating a path toward HIV vaccine development 2010
Stopping Dengue in its tracks 2010
Identifying and understanding rare immune system diseases 2001
Discovering new tuberculosis drugs 2000
In the fight against viral hepatitis A, vaccines save lives 1995
Advancing early, rapid diagnosis of river blindness 1991
Protecting at-risk children from a severe respiratory disease 1989
First detection and screening of the HIV virus 1985
Hitting HIV hard with HAART therapy 1985
Demonstration that HTLV-III is the causative agent of AIDS 1984
Discovery of the disease agent causing Lyme disease 1981
Discovery of the first human retroviruses 1980
Developing the first rotavirus vaccine 1974

Substance Abuse

FDA-approved heart medication shows promise as treatment for alcohol use disorder 2022
Two distinct mechanisms drive severe alcoholic liver disease 2022

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