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The Body
Blood and Lymphatic System
Autoimmune antibodies cause life-threatening blood clots in COVID-19
2020
Changes in blood proteins indicate aging trajectories
2018
Rethinking how the brain removes waste
2017
Creating a blood test to predict recurrence of a common lymphoma
2015
Donor telomere length affects survival after hematopoietic cell transplantation for severe aplastic anemia
2015
Bones, Joints, and Muscles
Identifying RNA changes in skeletal muscle related to healthy aging
2021
A new view of how muscles generate movement
2020
Wearable robotic exoskeleton improves walking posture in children with cerebral palsy
2017
Brain and Nervous System
Exploring the structure and function of an epilepsy-related ion channel
2023
Understanding how endocannabinoids in the brain help extinguish fear
2023
Arthritis medications may lower risk for Alzheimer’s disease in certain patients
2022
Activating brain cells that alleviate pain
2021
Bile acids in the brain provide a potential treatment target for Alzheimer’s disease
2021
Defining a spine-to-brain pathway that drives pain
2021
New insights into the molecules and neurons responsible for the sense of touch
2021
Revealing new genetic variants associated with Lewy body dementia
2021
Searching for signs of COVID-19 infection in the brain
2021
Brain’s sensory regions play a role in fentanyl relapse
2020
Highly selective compound could treat neuropsychiatric disorders with fewer side effects
2020
How a rare epilepsy-associated mutation disrupts neuronal communication
2020
How our internal clock tells us when it’s time for lunch
2020
How the brain powers communication between neurons
2020
Identifying reproducible sex-based differences in the human brain
2020
Identifying the cellular basis of altered brain function in long-term cannabis users
2020
Zebrafish studies reveal molecular and cellular determinants of motor asymmetry
2020
Coordinated ‘ripples’ of brain activity signal successful memory retrieval
2019
Discovering the surprising effects of the brain’s stress chemical
2019
Highly potent binding molecules improve imaging and activation of lab-designed neuronal receptors
2019
Neuron-specific genome modification in the adult rat brain using CRISPR-Cas9
2019
Sticky protein boosts neuronal receptor’s response to anti-anxiety drugs
2019
Understanding the ups and downs of pain modulation
2019
A brainstem-spinal circuit controlling movement in response to pain
2018
A sneak peek into the social brain: miniScope imaging reveals neural coding of social behavior
2018
How paying attention helps improve our memory
2018
Nicotinamide riboside (NAD+) prevents DNA damage and shows cognitive benefits in preclinical model of Alzheimer’s disease
2018
Organization of bigger brains shows how thinking drives brain development
2018
Pair of proteins repairs cellular highway system
2018
Point-of-care diagnostics: a blood biomarker to diagnose mild traumatic brain injuries
2018
Somatostatin: a key factor in the transmission of itch and pain
2018
Tracing pathways in the brain to understand how light affects mood and learning
2018
Understanding key components of the brain’s stress circuitry
2018
Antibodies to infections can cause neurological disorders
2017
Biomarker in blood may predict recovery time after sports concussion
2017
Chemogenetics revealed: converted clozapine activates lab-designed neuronal receptors
2017
How cells combat prions and amyloids
2017
Immune cells mediate the repair of blood vessels following traumatic brain injury
2017
Mitochondria power neuronal axon growth and regeneration
2017
Noninvasive imaging technique tracks brain activity with pinpoint precision
2017
Skill learning encoded via brain’s parallel processing in cortex and striatum
2017
A method of unraveling neural encoding mechanisms
2016
Amygdala is as important as the ventral striatum for reinforcement learning
2016
Better techniques for untangling correlations in big fMRI data
2016
Discovery of a new protein triaging pathway for neurotoxic proteins
2016
Finding molecular signatures of Alzheimer’s disease in blood extracellular vesicles
2015
Watching deep-brain movement circuits in action
2015
Alzheimer’s disease: challenging the amyloid dogma
2013
Detecting brain changes years before Alzheimer’s disease onset
2013
Finding the key to dendritic spine development
2013
Itching for an answer
2013
Mapping the adult mouse brain using embryonic gene expression
2013
Mind-body practices and yoga may protect against neurodegenerative effects of chronic pain
2013
New views of emotional regulation and decision making
2013
Fission and fusion to help keep our cells healthy
2012
How voltage ion channels interact with their surroundings
2009
Yeast proteins teach us about Alzheimer’s disease
2008
Moving toward understanding polyglutamine toxicity
2001
Understanding the breathing rhythm: respiratory pacemaker neurons located in the brain
1999
The first understanding of how brain cells communicate
1970
Digestive System
Infections train the microbiome to defend against future threats
2021
Mapping irritable bowel syndrome
2014
Creating a new method to measure abdominal pain
2010
Ear, Nose, and Throat
Linking genetic mutations to two rare facial conditions
2017
Guarding against hearing loss from anti-cancer drugs
2014
Understanding deafness: the role of auditory nerve mapping
2012
Endocrine System (Hormones)
Hunting for disease-causing genetic variants in non-coding DNA
2023
Gestational diabetes provides a warning sign for increased risk of chronic diseases later in life
2018
Hormones boost gene activity through super enhancers
2016
Taking a closer look at our on/off relationship with insulin
2012
Tracking the devastating effects of diethylstilbestrol (DES), a trans-placental carcinogen
2011
Eyes and Vision
Artificial intelligence improves diagnosis and risk prediction for vision-destroying disease
2022
Unraveling a complex world of neuronal connections
2011
Anatomy of Perception: Identifying Two Visual Streams in the Brain
1982
Heart and Circulation
Open SESAME: Heart surgery without the surgery
2024
3D organ model shows cadmium exposure in pregnancy may affect heart development
2022
Combining CT scans with artificial intelligence to assess cardiovascular health
2021
Designer drug for lowering triglycerides
2020
Using artificial intelligence to better predict heart attacks, strokes, and death
2020
Discovering a link between genetics and high blood pressure in African Americans
2019
Mechanism of age-associated failure of the heart’s pacemaker
2018
New therapy provides faster treatment for heart attacks
2018
Salt intake and sodium pump inhibitor linked to aortic stiffening and cardiovascular diseases
2018
Linking psoriasis inflammation and treatment with risk for cardiovascular disease
2017
Immune System
Protecting damaged tissues with immunomodulatory biomaterials
2023
A new view of immune responses to fungal diseases
2021
Exploring how fasting blunts inflammation
2021
Uncovering new aspects of a cellular danger system involved in inflammatory diseases
2021
A different delivery route may improve tuberculosis vaccine effectiveness
2020
New insights into the cell’s cleaning system
2020
A new treatment for a rare blood disorder
2019
High sugar intake worsens autoimmune disease in mice
2019
How periodic calorie restriction bolsters the immune system
2019
New insights into the role of mitochondria in autoimmune diseases
2019
Organisms that live on your skin help heal your wounds
2019
Wild microbes make lab mice more accurate models for human immune studies
2019
Insights into influenza through human challenge
2016
Dissecting the immune response
2015
Learning that cells can use their nuclei like pistons to move
2014
Programmed cell death drives generation of immune system’s regulatory T cells
2014
Discovering monogenic forms of common variable immunogenicity
2012
Reclassification of diseases improves understanding and outcomes
2011
Discovery of interleukin-2 (IL-2)
1976
Kidney and Urinary System
How you know when to go: identifying the mechanisms of bladder sensation
2020
Understanding health disparities in kidney disease
2010
Lungs and Breathing
Boosting immune cells to fight pneumonia without antibiotics
2021
Mental Health and Behavior
Uncovering the cellular causes of anxiety due to social stress
2021
Identifying patterns of depression in new moms
2020
Wearable technology revolutionizes symptom monitoring and treatment for bipolar disorder
2019
Ketamine for the treatment of depression and other anxiety-related disorders
2016
Identifying a key neurological regulator of social memory and aggression
2014
Understanding sensory symptoms in autism: seeing the trees, but not the forest
2014
Exploring racial differences in antidepressant response
2013
Identifying an Alzheimer’s disease risk gene
2013
Spur of the moment purchase? Blame your orbitofrontal cortex
2012
Stimulating new ideas on caffeine action in the brain
2011
The need for speed: A new approach to treating depressive disorders
2010
Could you become addicted to something? Your genes reveal all
2008
First successful treatment of childhood schizophrenia
1994
First successful treatment of childhood OCD
1985
A sense of calm in bipolar disorder: The clinical trials of lithium
1970
Mouth and Teeth
A targeted approach for treating Sjögren’s syndrome
2020
Immune cells linked to new model of gum disease
2018
Reproduction and Sexual Health
Battle of the sexes: when the female embryo takes control
2017
Delaying pregnancy: can we test how fast the biological clock is ticking?
2017
How membrane fusion and fission occur in live cells
2017
Quantitative control mechanisms ensure the fidelity of cell division
2017
Skin, Hair, and Nails
Assessing topical treatments for eczema in 3D-biofabricated skin tissue
2021
Discovery of a rapid immune response to a dangerous skin infection
2021
Learning about human skin’s microbiota
2014
Only skin deep? New insights on retinoic acid in skin development
2012
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