The National Institutes of Health (NIH) campuses host a variety of events that inform, challenge, and unite the biomedical research community. IRP investigators lead or participate in many of these events, and they regularly present their work at scientific conferences at the NIH and around the world. We invite you to learn about (and possibly join us in) some of our upcoming events. Unless otherwise noted, times listed are Eastern Standard Time (EST).
Autopsies are an indispensable, although underutilized, tool for gleaning insight into human disease pathogenesis and treatment. In this talk, Dr. Chertow will discuss the application of advanced technologies, including quantitative PCR, sequencing, and high-dimensional phenotypic and transcriptomic cellular profiling of postmortem specimens collected from fatal COVID-19 cases. With these tools, Dr. Chertow's research provides novel insights into pathogen distribution, persistence, evolution, and host cellular and transcriptional responses within tissues.
Dr. Werner's lab studies the molecular principles of how cell-fate decisions are determined during development. Its studies focus on ubiquitylation, an essential posttranslational modification that is required for cell division, differentiation, and migration in all metazoans. His group leverages the unique environment of the NIH intramural program and combines human pluripotent stem cell culture, proteomics, and ubiquitin biochemistry with animal models, clinical genetics, and human disease cohorts. In this lecture, Dr. Werner will summarize how this integration of expertise with his local colleagues has allowed his team to uncover mechanisms of how ubiquitylation regulates diverse aspects of neuroectodermal and hematopoietic differentiation and to define previously unrecognized neurodevelopmental, craniofacial, and autoinflammatory diseases.
Lipsett Amphitheater, NIH Clinical Center (Building 10); or online via NIH Videocast
This NIH Astute Clinician Lecture — part of NIH's Wednesday Afternoon Lecture Series (WALS) — will be presented by IRP Distinguished Investigator Mariana Kaplan, M.D. Her research in NIH's Systemic Autoimmunity Branch combines natural history and treatment studies with basic investigations into the etiology and pathophysiology of rheumatic diseases, including systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). In addition to her research activities, Dr. Kaplan is an active clinician and teacher. She sees lupus patients in the NIH Clinical Research Center and is involved in the development of various clinical trials for patients with autoimmune diseases at NIH.
The annual Astute Clinician Lecture was established in 1998 through a gift from the late Dr. Robert W. Miller and his wife, Haruko. It honors U.S. scientists who have observed unusual clinical occurrences and, by investigating them, have opened an important new avenue of research. The lectureship exemplifies how astute clinical observations can lead to innovative research.
The goal of the NCI RNA Biology Initiative is to establish a collaborative environment that promotes the swift exchange of information and expertise regarding the structure, function, and biological significance of RNA. Our objective is to leverage this collective knowledge to advance the development of novel diagnostics and therapies. We actively foster synergistic collaborations among NCI and NIH intramural investigators, as well as between our researchers and the broader RNA community.
The symposium offers the opportunity to learn more about the current status of RNA biology in development and disease, share research, network with leading figures in the field and discuss the use and implications of these advances for clinical applications.
Organized by the NCI RNA Biology Initiativethis symposium will bring together internationally renowned experts in the field of RNA biology, with the focus on:
RNA Processing
RNA Structure and Mechanism
Non-classical RNAs
RNA Therapy
This page was last updated on Friday, October 20, 2023