Monday, June 22, 2015
When it comes to devising new ways to provide state-of-the art medical care to people living in remote areas of the world, smartphones truly are helping scientists get smarter. For example, an NIH-supported team working in Central Africa recently turned an iPhone into a low-cost video microscope capable of quickly testing to see if people infected with a parasitic worm called Loa loa can safely receive a drug intended to protect them from a different, potentially blinding parasitic disease.
Saturday, June 20, 2015
Only one building was restricted during the 1951 NIH open house—Building 7, specially designed for infectious disease research. Children under 16 were not admitted. And there was only one demonstration: Dr. Karl Habel of NIH's National Institute of Allergy and Infectious Diseases (NIAID) showed the special procedures necessary in the collecting and handling of material for research on and vaccine development for rickettsial diseases carried by ticks. In this photo, is Dr. Habel following his own advice?
Monday, June 15, 2015
If 580 posters displaying scientific data from research across the intramural programs at 24 NIH Institutes and Centers sounds like a lot to take in, have a look at the size of the crowds coming to see them. Walking into the Natcher Conference Center on Postbac Poster Day is like walking into a maze abuzz with urgency. Bulletin board after bulletin board of postbac research posters summarize months of work, each one surrounded by fellow scientists, NIH staff, and visitors staff who are interested in the research and asking questions.
Friday, June 12, 2015
In 1951, Dr. Robert Bowman showed visitors to NIH’s Building 3 his prototype of a device that scanned wavelengths of fluorescent light emitted from various samples. Bowman’s spectrophotofluorometer, or “SPF,” allowed scientists to use fluorescence as a way to identify and measure tiny amounts of substances in the body. This scientific breakthrough is still used today.
Wednesday, May 20, 2015
If you’ve ever skipped meals for a whole day or gone on a strict, low-calorie diet, you know just how powerful the feeling of hunger can be. Your stomach may growl and rumble, but, ultimately, it’s your brain that signals when to start eating—and when to stop. So, learning more about the brain’s complex role in controlling appetite is crucial to efforts to develop better ways of helping the millions of Americans afflicted with obesity.
Monday, May 18, 2015
As a child I liked robots. Growing up in Korea, I liked cartoons and movies where people were on a mission to save the world with the robots they invented, and I wanted to develop a superhero robot someday, too. While my robot isn’t yet complete, the path I followed in pursuit of my goals eventually led me to explore data analysis.
And here I am, a postdoc at the NIH—probably the largest healthcare research institution in the world—in the Imaging Biomarkers and Computer-Aided Diagnosis Laboratory led by Dr. Ronald M. Summers. Our lab is part of the Department of Radiology and Imaging Sciences at the NIH Clinical Center.
Friday, May 8, 2015
Using real-time MRI, Dr. Keith Horvath's group at the NIH's National Heart, Lung, and Blood Institute (NHLBI) can precisely implant a replacement porcine heart valve using a collapsible stent more safely and quickly than with standard techniques.
"The reason for using [real-time] MRI is three-fold," Dr. Horvath explains...
Monday, May 4, 2015
When I was growing up, my grandfather would visit and try to teach me thermodynamics. At the time, I thought that this was normal conversation between a grandfather and a little girl. It was several years before I realized that he was an eminent scientist in his home country. My grandfather would always ask me, “How is your science?”
Monday, April 20, 2015
Ever since the discovery of the double-helix structure of DNA, scientists have sought ways to edit the genome. Altering gene expression partially and transiently via small interfering RNA has come a long way, and the progress has been spectacular. However, achieving complete and sustained modification of gene expression in a cell remains a tedious procedure that is often costly and time-consuming. For molecular biologists working with cell lines, quick and efficient knock out of one or more genes would provide a powerful tool for their studies. The CRISPR technology arrived two years ago to potentially fulfill that need.
Monday, April 13, 2015
Monitoring cell movement. Examining the microenvironment of a tumor. Mapping a gene. Scientists at the NCI Center for Cancer Research (CCR)—the intramural research program at the National Cancer Institute—use a wide variety of microscopy techniques to observe and probe the otherwise invisible processes that drive cancer at the molecular level.