vaccine

Creating Cutting-Edge Cancer Vaccines

IRP Research Identifies a Tantalizing Target for Cancer Immunotherapy

person getting vaccine injection

February 4 is World Cancer Day, a time to mark international efforts to prevent, detect, and treat cancer. Immunotherapy, one of the most significant advances in treating cancer, was pioneered here at NIH more than 30 years ago. Today, IRP senior investigator Claudia M. Palena, Ph.D., is pushing cancer immunotherapy forward with the discovery of a novel target for cancer vaccines.

IRP Researchers Tackle Coronavirus Crisis

New Studies Will Help Efforts to Contain and Treat COVID-19

coronavirus in a patient sample

Most of the time, science is a slow process, with many experiments taking years to yield results. However, as endeavors like the Manhattan Project have shown, scientists can dramatically accelerate the pace of discovery when necessary. Over the past few months, the novel coronavirus pandemic has spurred a burst of research from scientists around the world, including numerous IRP studies. Read on for a round-up of the latest IRP COVID-19 research and learn how IRP investigators are assisting in the fight against the novel coronavirus.

Remembrances: Alexis Shelokov (1919–2016)

Alexis Shelokov

Alexis Shelokov, who studied the polio virus at the NIH in the 1950s and was a powerful scientific force in what would become the famed NIAID Laboratory of Infectious Diseases in Building 7, died on December 16, 2016, in Dallas, Texas. He had a prolific scientific career that took him around the world.

Launchpad for Discovery: NIH’s Postbac IRTA Experience

With plans to travel to Swaziland and volunteer with the Baylor International Pediatric AIDS Initiative (BIPAI) and a desire to address issues related to health disparities in the treatment of HIV/AIDS, I began navigating the unfamiliar terrain of life after college.

Johnetta at George Mason graduation

Taking a “Moonshot” at Cancer

In his recent State of the Union address, President Barack Obama called America to action and asserted that our researchers can find the cure for cancer, a sentiment that received a standing ovation. We believe that Obama is right.

Presidential NIH Visits: Bill Clinton, 1999

The NIH is "one of America's great citadels of hope, not only for our people, but also for the world," said President Bill Clinton at the dedication of the Dale and Betty Bumpers Vaccine Research Center (VRC) on June 9, 1999.

President Bill Clinton with Senator Dale Bumpers at NIH VRC

Early Vaccine Research: Rickettsial Diseases in 1951

Only one building was restricted during the 1951 NIH open house—Building 7, specially designed for infectious disease research. Children under 16 were not admitted. And there was only one demonstration: Dr. Karl Habel of NIH's National Institute of Allergy and Infectious Diseases (NIAID) showed the special procedures necessary in the collecting and handling of material for research on and vaccine development for rickettsial diseases carried by ticks. In this photo, is Dr. Habel following his own advice?

Karl Habel, NIH NIAID

President Obama Visits Ebola Vaccine Lab as Women Make History

The Ebola vaccine developed by Dr. Nancy Sullivan at NIAID is a Women’s History Month highlight: women developed the vaccine and coordinated and led the clinical trial, and a woman was the first volunteer to receive the vaccine. “That wasn’t planned, but it’s kind of remarkable,” said Sullivan. She explained her work to President Barack Obama in person.

Sullivan with Obama

Women's History: 1930s Meningitis Research

Robert Forkish and Sara Branham

“Know your enemy” describes the work of Dr. Sarah Branham (1888-1962). She dedicated much of her career to understanding meningitis, identifying different strains, and developing the effective tests and treatments for the disease in anti-serum and sulfa drugs.

In this September 1937 photo, Branham and technician Robert Forkish inoculate a mouse with meningococcus antiserum to determine whether it will protect against meningitis:

The Power of Vaccines Research

Long recognized as essential to global health, vaccines protect individuals and populations from contagion and the reappearance of eradicated diseases. Vaccination against deadly diseases prevents two to three million deaths worldwide every year, and there are significant economic benefits as well. In the United States, every dollar spent on the routine childhood immunization program saves society more than $16 in future costs.

HPV vaccine molecule