Budding Scientists Present Their Research During Three-Day Virtual Event
Monday, August 30, 2021
Although NIH’s 2021 Summer Internship Program (SIP) was fully virtual this year, that didn’t stop the hundreds of participating high school, college, and graduate students from contributing to a variety of important IRP research projects. More than 500 students who worked in NIH labs this summer presented their work during this year’s Summer Presentation Week, which took place August 3-5.
I sifted through the lengthy list of presenters at the event and spoke with a diverse group of young men and women who spent their summers expanding our knowledge of human health and biology. Read on to learn about these promising future scientists and doctors and the research they completed this summer.
Approach Could Protect or Even Regenerate Neurons in Eye and Spinal Cord
Tuesday, August 24, 2021
At the end of Aesop’s fable The Lion and the Mouse, the titular rodent saves his much larger friend from a hunter’s trap. Just like Aesop, scientists know well that even something tiny and often overlooked can lend a helping hand. Extremely short strands of genetic material called microRNAs, for instance, could make for useful therapeutic targets for glaucoma and other degenerative eye ailments, according to new IRP research.
Individuals From Around the World Drive IRP Breakthroughs
Wednesday, August 11, 2021
Come to NIH and you’ll hear many accents. Scientists from around the world have always contributed significantly to the NIH mission. The resulting diversity of backgrounds and perspectives makes the NIH Intramural Research Program an extremely stimulating and productive environment. Read on to learn about some of the many scientists of the past and present who brought their talents from abroad to one of the world’s leading institutions for biomedical research.
Human and Animal Studies Point to New Treatment Strategy
Tuesday, June 8, 2021
Interest in the low-carb ‘ketogenetic’ diet has exploded in recent years, with legions of enthusiasts jumping on the bandwagon. The popular dietary regimen has even caught the attention of scientists seeking new treatments for an array of health conditions. For instance, a recent IRP study suggests that a ketogenic diet might make it easier for people with alcohol use disorder to stop drinking.
New Receptors and Radioactively Labeled Molecules Could Provide Useful Tools for Research and Medicine
Wednesday, March 17, 2021
Genetically modifying neurons to enable scientists and clinicians to influence brain activity probably sounds like the stuff of science fiction. However, the technology has existed for more than a decade, allowing scientists to make important leaps in understanding how neurons communicate with one another in healthy individuals and those with psychological and neurological conditions. What’s more, recent improvements to these tools developed by researchers led by IRP investigator Mike Michaelides, Ph.D., may allow neurologists to use them to deliver drugs to just the right brain cells to treat those ailments effectively without the side effects caused by current treatments.
Virtual Symposium Showcases Scientists-in-Training
Monday, March 8, 2021
Even in the midst of a global pandemic, life at NIH goes on. IRP researchers continue to run experiments, publish scientific papers, and train the next generation of scientists, including the many graduate students performing research in IRP labs through the Graduate Partnership Program. On February 17 and 18, more than 100 of these scientists-in-training presented their work virtually at the NIH’s 17th annual Graduate Student Research Symposium. Like last year’s entirely online Postbac Poster Day, the event overcame the constraints of COVID-19 precautions to showcase a broad range of research, including several studies focused on the novel coronavirus.
Biomarker Discovery Could Aid Diagnosis and Therapeutic Development
Tuesday, February 16, 2021
Our cells can’t afford to be wasteful, so they prefer to recycle broken components. However, when the mitochondria that provide their energy are damaged beyond repair, cells may have no choice but to throw them out. New IRP research suggests that more of this mitochondrial debris floats in the blood of patients with Alzheimer’s disease, potentially providing an easy, cost-effective way to diagnose or even possibly predict the illness.
NIH Researcher Recognized for Advances in Brain Imaging
Tuesday, November 17, 2020
The National Academy of Engineering (NAE), established in 1964, comprises more than 2,000 peer-elected members who are among the world’s most accomplished engineers, including senior professionals in business, academia, and government.
IRP senior investigator Peter Basser, Ph.D., was elected to the NAE in February 2020. He directs the Section on Quantitative Imaging and Tissue Science and the Division of Translational Imaging and Genomic Integrity in the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), where he studies how the structure and material properties of living tissues affect their function.
Genetic Studies Illuminate Neuronal Chemical’s Role in Pain and Itch
Thursday, October 29, 2020
For most of us, itch is a bothersome inconvenience. Unfortunately, for 125 million people around the world, chronic itch caused by the skin disease psoriasis is a significant, even debilitating, health problem. Psoriasis causes skin cells to multiply up to 10 times faster than normal and build up as an itchy and painful, scaly rash. For some, the condition can also cause joint swelling, resulting in a condition known as ‘psoriatic arthritis.’
World Psoriasis Day falls on October 29 this year, and the theme is “Be Informed.” So, what do we know about chronic itch?
‘Silicon Valley Nobel’ Recognizes Groundbreaking Parkinson’s Disease Research
Tuesday, October 6, 2020
It can be easy to underestimate the value of so-called ‘basic science’ that doesn’t appear, upon first glance, to have clear therapeutic applications. One of the hidden strengths of this sort of work is its ability to link seemingly disparate areas of scientific inquiry by identifying commonalities between the structure or behavior of different biological molecules. By following these unexpected connections over the course of his career, IRP senior investigator Richard Youle, Ph.D., has made critical discoveries about Parkinson’s disease — research that this year earned him the prestigious Breakthrough Prize in Life Sciences.