Tuesday, May 17, 2016
You may already know that diet, obesity, exposure to the sun, radiation, and hormones are just a few of the many risk factors associated with cancer diagnoses. But, do you know about other risk factors, especially those playing out through epigenetics, the molecular relationship between the environment and our DNA? Read more...
Monday, April 25, 2016
Six months after turning two, Eli Palmer still wasn’t walking, and his parents, Julie and Seth, had begun to worry. But they figured their fourth child was growing at his own pace and would soon catch up.
Tuesday, March 29, 2016
Annaleise Knight is an active, outgoing six-year-old. In her hometown of Grayslake, Illinois, she loves riding her bike, swimming, taking ballet and tap lessons, and playing outside on the swings and trampoline with her three siblings, Nicholas, 16, Braden, 7, and Catherine, 4. Although Annaleise has an exuberant personality, she did not always have the energy and strength to do her favorite activities.
Saturday, October 31, 2015
October is National Breast Cancer Awareness month, four weeks out of the year dedicated to bringing visibility and awareness to research in support of one of the most widespread and devastating cancers in existence.
Wednesday, August 12, 2015
You never know when inspiration will strike. I still remember the day that Dr. Francis Collins came to visit my high school genetics class. At that time, Dr. Collins was the director of the Human Genome Project, an international research program aimed at uncovering the genetic building blocks essential for human life. Imagine our recent excitement when Dr. Collins, now Director of the NIH, specially attended a reception for clinical fellows at the Clinical Center.
Monday, June 1, 2015
What is a rare disease? And how rare is “rare”? When I began my research at the NIH, I had a textbook understanding of rare diseases, but now, after four years as a postdoc in the IRP, I understand a bit more of what it means to the patients and researchers who try to help them.
Wednesday, May 20, 2015
If you’ve ever skipped meals for a whole day or gone on a strict, low-calorie diet, you know just how powerful the feeling of hunger can be. Your stomach may growl and rumble, but, ultimately, it’s your brain that signals when to start eating—and when to stop. So, learning more about the brain’s complex role in controlling appetite is crucial to efforts to develop better ways of helping the millions of Americans afflicted with obesity.
Monday, April 20, 2015
Ever since the discovery of the double-helix structure of DNA, scientists have sought ways to edit the genome. Altering gene expression partially and transiently via small interfering RNA has come a long way, and the progress has been spectacular. However, achieving complete and sustained modification of gene expression in a cell remains a tedious procedure that is often costly and time-consuming. For molecular biologists working with cell lines, quick and efficient knock out of one or more genes would provide a powerful tool for their studies. The CRISPR technology arrived two years ago to potentially fulfill that need.
Monday, December 15, 2014
During my Ph.D., I decided to pursue my thesis project in a lab working in the RNA field and, more specifically, on the mechanisms of alternative splicing regulation. Moving onto my post-doctoral training, I decided to stay in this field mainly because I found it fascinating to work with RNA. It is such a flexible and diverse molecule, but also largely unexplored. I believed that this relatively new area of research would attract more interest among scientists, and the last few years show that I was thinking in the right direction.