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I am Intramural Blog

Untangling Alzheimer’s Disease — Searching for Biomarkers in Exosomes

Thursday, September 29, 2016

What if we could diagnose risk for Alzheimer’s before symptoms appeared? To address the challenge, in the Laboratory of Neurosciences at the IRP, Dr. Maja Mustapic searches for Alzheimer’s biomarkers using liquid biopsies.

Untangling Alzheimer’s Disease — Longitudinal Human Neuroimaging

Thursday, September 22, 2016

Murat Bilgel, NIH IRP postdoc, at his desk with brain scans

“The goal of my project is to study these earliest stages of Alzheimer’s disease by constructing a timeline of changes in brain imaging and cognitive measures related to Alzheimer’s in a group of cognitively normal individuals,” postdoc Murat Bilgel explains.

Untangling Alzheimer’s Disease — DNA Damage in Alzheimer’s

Tuesday, September 20, 2016

Given that Alzheimer’s is such a complex disease with many causes and pathways, it is not surprising that the search for effective treatments has proven difficult. So I spoke with Drs. Yujun Hou and Hyundong Song, postdoctoral fellows in the IRP’s Laboratory of Molecular Gerontology at the National Institute on Aging (NIA) to learn more about their approaches to meeting the challenge.

Untangling Alzheimer’s Disease — September is Alzheimer’s Awareness Month

Thursday, September 15, 2016

Inspired by September’s World Alzheimer's Awareness Month and driven by my interest in cognitive aging and dementia, I'm asking my fellow IRP postdoctoral researchers about which approaches they believe hold promise for advancing our understanding of Alzheimer’s disease.

Exercise Releases Brain-Healthy Protein

Thursday, June 30, 2016

Five images of different exercise activities

We all know that exercise is important for a strong and healthy body. Less appreciated is that exercise seems also to be important for a strong and healthy mind, boosting memory and learning, while possibly delaying age-related cognitive decline. How is this so? Researchers have assembled a growing body of evidence that suggests skeletal muscle cells secrete proteins and other factors into the blood during exercise that have a regenerative effect on the brain.

Neuronal Trees in Holiday Colors

Friday, December 26, 2014

These may remind you of trees on a winter day, but they are brain neurons grown in a special chamber that separates axons from dendrites.