NEI Researchers Use Geckos and Other Lizards to Accelerate Clinical Vision Research
The go-to lab animals to study many human eye diseases tend to be mammals—a mouse or a rat for example—because of their similar evolution and genetics compared to humans. But for diseases that affect a part of the eye called the fovea, which provides high-acuity central vision in humans, scientists are beginning to look further afield...to geckos.
The NIH Catalyst was launched 30 years ago and is still going strong. During this year, The NIH Catalyst will be highlighting some of the stories that appeared in the earlier years and compare them with what’s happening now.
Former NIH Clinical Center Director Reflects on His Career at NIH
John Gallin, who is retiring in March 2023 after 52 years at NIH, has been an Editor for The NIH Catalyst since it began in 1993. Here he talks with the Catalyst about his involvement with the publication and about his own career.
Scientists Explore Links Between Hydration and Aging
Legend has it that Spanish conquistador Juan Ponce de León scoured the Caribbean and Florida for the fabled fountain of youth. He never found it. In a twist of fate, he died prematurely from wounds sustained during a skirmish with native warriors. Could an antiaging elixir exist today? Perhaps look no further than a glass of water.
Primary Care Leader to Improve Accessibility and Inclusivity
The National Institute of Nursing Research (NINR) welcomed Sabrina Wong as its new Scientific Director (SD) in September 2022. A scholar and international leader in primary-care research, she brings her passion for reducing inequities in health and health care and a long-standing interest in the organization and delivery of primary health care services.
Inventing new ways to thwart viruses and treat diseases; developing early-detection methods for cancer; investigating the connection between neural circuitry and obesity; finding ways to reduce health disparities. These are just some of the challenges that the Earl Stadtman Tenure-Track Investigators have taken on. Meet 18 of them here.
Rory Cooper knows wheelchairs. He’s been using them since he was 20, after a bicycle accident in 1980 while serving in the U.S. Army in Germany left him with a spinal injury limiting the mobility of his legs. He knows that making better wheelchairs for those who depend on them can unlock human potential otherwise constrained for lack of accessibility and inclusion.
“Less than 2% of human genomes analyzed so far have been those of African people, despite the fact that Africa, where humans originated, contains more genetic diversity than any other continent,” medical geneticist Ambroise Wonkam wrote in a Nature commentary (Nature590:209-211, 2021). He explained further at a Wednesday Afternoon Lecture last September that “to make genetic medicine truly equitable, we need to have representation of a wide genome [by starting] with our common ancestral genomes—genomes of the population of African ancestry.”