IRP Scientists Keep it Short and Sweet in Competition’s Final Round
Wednesday, July 7, 2021
Science is so closely associated with long, jargon-laden lectures that scientists like Neil deGrasse Tyson and the IRP’s own Anthony Fauci have become celebrities for their ability to explain complex scientific concepts in a succinct and understandable way. On June 25, 17 postbacs, graduate students, and postdocs from across NIH showcased their own communication chops in the final round of the IRP’s annual Three-Minute Talks (TmT) competition.
Human and Animal Studies Point to New Treatment Strategy
Tuesday, June 8, 2021
Interest in the low-carb ‘ketogenetic’ diet has exploded in recent years, with legions of enthusiasts jumping on the bandwagon. The popular dietary regimen has even caught the attention of scientists seeking new treatments for an array of health conditions. For instance, a recent IRP study suggests that a ketogenic diet might make it easier for people with alcohol use disorder to stop drinking.
IRP Research Overturns Common Concerns About ‘Weight Cycling’
Tuesday, December 8, 2020
With 2021 less than a month away, many of the more than 200 million Americans who are overweight or obese are beginning to consider making weight loss their New Year’s resolutions — perhaps not for the first time. While trying to lose weight only to ultimately regain it may be disappointing, a new IRP study suggests that repeated attempts at weight loss significantly reduce a person’s risk of dying.
Mouse Study Identifies Neurological Obstacle to Dietary Improvements
Tuesday, September 15, 2020
Every morning, thousands of Americans wake up intending to eat more healthfully, only to find themselves chowing down on a greasy burger at dinnertime. In addition to the many biological and socioeconomic obstacles to healthy eating, a salad can just plain seem unappealing compared to a plate of crispy fries. According to new IRP research, a high-fat diet can dramatically alter how the brain responds to food in ways that make a more wholesome meal less enticing and satisfying.
Tuesday, September 11, 2018
Between fast-food outlets, vending machines, and food trucks — not to mention good old-fashioned home cooking — many people face no shortage of opportunities to eat. But as satisfying as a crisp potato chip or a moist pork chop may be, people with asthma and many other conditions may prefer to resist tasty temptations if it means alleviating some of their symptoms. In a small pilot study, IRP researchers found evidence that abstaining from food for 24 hours could inhibit some of the cellular processes that cause asthmatics’ breathing problems.
Thursday, August 16, 2018
Upon entering the sunny foyer of the NIH’s Natcher Conference Center last Thursday, I was immediately struck by a burst of loud, excited chatter. As it always is on NIH’s annual Summer Poster Day, the building was filled with hundreds of high school and college students and the scientists, families, and friends who had turned out to see what these young men and women had spent the summer doing.
Tuesday, March 13, 2018
Food companies have long marketed carbohydrate-rich drinks and energy bars to athletes with the message that the energy those snacks provide is key to lifting heavier and running farther. A new mouse study by IRP researchers, however, suggests that skipping a meal (or several) might be far more effective for increasing athletic prowess1.
Unlike modern Americans used to three square meals a day, our ancient ancestors couldn’t exactly throw a TV dinner in the microwave whenever they felt a bit peckish. As a result, they probably found themselves hunting wooly mammoths and fending off saber-toothed tigers on an empty stomach.
“From an evolutionary perspective, animals in the wild – particularly predators – need to be able to function at a high level when they’re in a food-deprived state,” says IRP Senior Investigator Mark P. Mattson, Ph.D., the study’s senior author. “Individuals who were able to perform at a high level in a fasted state had a survival advantage.”
Tuesday, February 13, 2018
Researchers have a long history of fattening up mice to gain insight into the causes and consequences of weight gain in the human body. In one of the more recent studies of this kind, a team of IRP researchers found that that a high-fat diet consistently altered the collection of microbes residing in mice’s digestive tracts and that this diet-microbe combination might pre-dispose the mice – and, potentially, obese humans – to colon cancer by triggering certain changes in how genes behave.
Tuesday, May 16, 2017
The struggle to maintain a healthy weight is a lifelong challenge for many of us. In fact, the average American packs on an extra 30 pounds from early adulthood to age 50. What’s responsible for this tendency toward middle-age spread? For most of us, too many calories and too little exercise definitely play a role. But now comes word that another reason may lie in a strong—and previously unknown—biochemical mechanism related to the normal aging process.
Thursday, December 15, 2016
Yasmine Belkaid, chief of the Mucosal Immunology Section in the NIAID Laboratory of Parasitic Diseases, has won the Sanofi–Institut Pasteur 2016 International Mid-Career Award for “outstanding research in the life sciences…contributing to progress in global public health,” announced on December 13, 2016 in Paris.