clinical trials

Wearing Your Heart on Your Sleeve—1970s Style

This dapper bee from 1977 advertised an NHLBI-sponsored multicenter, randomized, double-blind, and placebo-controlled trial designed to test the benefits of beta-blockers for people who had had a heart attack. The study was called the Beta-Blocker Heart Attack Trial (BHAT). Ah, you say—that’s why the bee in the hat!

Yellow pin with illustration of a bee holding a flower and wearing a top-hat with the word “BHAT”

NIH Nurses Play Critical Roles in Cancer and Ebola Discovery

In 2007, the NIH Clinical Center (CC) established two research nursing roles that are critical to the success of the many studies undertaken at the CC. Clinical Research Nurses (CRN) are staff nurses who focus on caring for research participants, while also providing support for studies in a clinical delivery setting. Research Nurse Coordinators (RCN) are responsible for managing research studies and enormous amounts of data collection. They are in charge of recruiting and enrolling participants, maintaining study consistency, and overseeing regulatory adherence.

NIH Special Clinical Studies Unit Nurse

Phoenix Rising to Obesity and Diabetes Research

Phoenix, Arizona, received its name from a British pioneer named Darrell Duppa. When he saw what was left of prehistoric settlements built by the Hohokam civilization thousands of years before his arrival, he knew that another great civilization would “rise from these ashes” just like the mythic bird. The desert city is today home to the Phoenix Epidemiology and Clinical Research Branch, one of six IRP research campuses.

PECRB Main Campus - NIH NIDDK

President Obama Visits Ebola Vaccine Lab as Women Make History

The Ebola vaccine developed by Dr. Nancy Sullivan at NIAID is a Women’s History Month highlight: women developed the vaccine and coordinated and led the clinical trial, and a woman was the first volunteer to receive the vaccine. “That wasn’t planned, but it’s kind of remarkable,” said Sullivan. She explained her work to President Barack Obama in person.

Sullivan with Obama

The Best Place on Earth

If you've been asking yourself what good your taxpayer dollars have been doing, let me tell you a story. I work at one of the most amazing places in the world. Every day I come in to work energized to see patients, to strategize how to bring new findings into the clinic and talk to brilliant scientists and physicians.

James Gulley and Patient at NIH

Fighting Obesity Every Which Way We Can

The solution to obesity seems simple on the surface—fewer calories in, more calories out—but for those who have tried to lose weight, it's usually not an easy task, partly because weight is the product of many interrelated factors: environment, family history and genetics, behavior, metabolism, and others. Investigators at the NIH Intramural Research Program (IRP) are studying all of those aspects and more to further understand the disease and better inform public health initiatives.