BY JENNIFER PATTERSON-WEST, NIDDK
Her colleagues laughed at her “crazy idea” when she was a graduate student at the University of California, Berkeley, in the 1980s. Gisela Storz had predicted that a single protein (OxyR) could sense a destructive oxidant, hydrogen peroxide, bind to DNA, and turn on genes that would neutralize the threat. But Storz has gotten the last laugh. Turns out that her hypothesis was correct.
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