Brandon Levy is a Health Communications Specialist for the NIH’s Intramural Research Program, where he works to increase the IRP’s public profile and ensure IRP scientists get the recognition they deserve. He particularly enjoys writing about the cutting-edge research performed at NIH but also produces videos and content for social media. Before joining the IRP, he worked as a science writer in NIH’s National Institute of Neurological Disorders and Stroke (NINDS) and as a postbaccalaureate Intramural Research Training Award (IRTA) fellow in NIH’s National Institute of Mental Health (NIMH), spending his days putting people inside giant magnets and sending magnetic waves into their brains to shed light on the mysteries of learning and memory. When he’s not hunched over a computer keyboard, Brandon enjoys singing in his acapella group, reading, honing his skills as an amateur chef, and over-obsessing about college basketball.
Mouse Study Demonstrates Promise of New Therapy for Rare Genetic Conditions
If you ask a scientist how old you are, you may be surprised to get a different answer depending on who you’re talking to. That’s because age can be measured both ‘chronologically’ — in terms of time — and at a cellular level. Indeed, certain genetic mutations cause cells to age faster, leading to a host of health problems. Fortunately, a recent IRP study performed in mice suggests that boosting levels of a specific molecule could help alleviate some of those patients’ symptoms.
Highlighting Drugs and Vaccines Stemming from NIH Discoveries
On May 3, more than six decades of IRP research culminated in the U.S. Food and Drug Administration (FDA) approving the world’s first vaccine for respiratory syncytial virus (RSV), a disease that puts tens of thousands of Americans in the hospital each year and kills thousands. While the new vaccine, called Arexy, has been getting all the headlines recently, it is only the latest example of a slew of FDA-approved medications and vaccines that might never have existed without the tireless efforts of scientists at NIH.
Indeed, a recently published study led by Mark Rohrbaugh, Ph.D., J.D., a special advisor in the NIH Office of Science Policy, found that inventions developed at NIH have contributed to more FDA-approved products than those created at any other nonprofit research institution in the world over the past five decades. NIH tops the study’s list with 27 FDA-approved products, six more than the study attributed to the combined efforts of all the schools in the University of California system.
Budding Scientists Assemble for First Time Since 2019
In many ways, working at NIH feels like being at a world-renowned university, complete with a variety of classes, intellectually stimulating lectures, social events, and opportunities for professional development. It’s no wonder, then, that NIH has long been a destination for young people who have just departed from their alma maters with their newly earned undergraduate degrees.
These new graduates come to the IRP to hone their scientific skills in NIH’s Postbac IRTA program, conducting research in IRP labs for one or two years under the expert guidance of the IRP’s seasoned investigators. The program also provides the opportunity once per year for participants to present the fruits of their efforts to all their IRP colleagues at Postbac Poster Day, and this year’s event on April 19 and 20 was the first to include an in-person component since 2019. Read on to learn about a few of the nearly 1,000 postbacs who showed off their research at this year’s event, which spanned fields from neuroscience and cancer to genetics and virtual reality.
There’s no doubt that science flourishes when it welcomes individuals with different backgrounds and perspectives. In pursuit of that goal, NIH has put considerable effort into closing the gender gap in the biomedical sciences, a field in which men significantly outnumber women, especially as the heads of labs and in leadership positions. Those efforts have so far yielded promising progress, with the proportion of women in IRP senior investigator positions increasing from 22 percent at the end of fiscal year 2016 to 27 percent at the end of fiscal year 2022. Over that same time period, women went from comprising 38 percent of IRP tenure-track investigators to 44 percent.
Part of what makes the IRP a welcoming place for female scientists is the NIH Women Scientists Advisors (WSA), a group of IRP scientists elected to represent the interests of women in the IRP. Once per year, the WSA selects a few female postdoctoral fellows or graduate students conducting research at NIH as WSA Scholars. At a symposium on April 13 honoring the achievements of this year’s Scholars, the awardees presented their efforts to learn more about a devastating childhood neurological condition, decrease health disparities in breast cancer, and use stem cells to investigate the roots of a nerve-destroying disorder. Read on to learn more about this year’s WSA Scholars and the important work they’re doing in their IRP labs.
Interrupting Sedentary Time Could Help Stave Off Health Problems
Many people don’t get much exercise these days, and kids are no exception. Whether at school, doing homework, or entertaining themselves online, children and teens spend hours on end sitting around. That lack of physical activity raises their risk for metabolic conditions like obesity and type 2 diabetes, but according to a recent IRP study, breaking up those long, sedentary periods with just a few minutes of exercise could yield noticeable benefits for their health.
IRP Study Points to Strategies to Stop Disease From Spreading
Ancient Greek myth describes how the hero Hercules battled the many-headed hydra, which regrew two heads every time Hercules cut one off. This frustrating fight against a seemingly invulnerable opponent would be an apt metaphor for treating cancer, in which tumor cells sometimes die in a particular way that actually helps their brethren multiply and spread to other parts of the body. In a study of that phenomenon using a mouse model of breast cancer, IRP researchers discovered that it occurs because that form of cell death suppresses the immune system’s response to the cancer,a finding that points to several potential ways to improve cancer therapy.
Study Suggests New Treatment Approach for Deadly Lung Infection
Oxygen is, quite literally, the air we breathe (or, more accurately, 21 percent of it). However, just as oxygen in the air can turn a handy garden tool into a useless hunk of rust, certain unstable, oxygen-containing molecules in our bodies can wreak havoc on our cells. According to new IRP research, revving up cellular systems that prevent this kind of damage could significantly improve outcomes for people with tuberculosis.
Event Includes In-Person Presentations for First Time Since 2020
Three years after COVID-19 dramatically changed the way scientists and many others work, much of life in the NIH IRP has begun to resemble the way things were in February of 2020. This includes the return of in-person scientific poster sessions like the one that took place on February 16 as part of the 19th annual NIH Graduate Student Research Symposium. Nearly 130 graduate students conducting their Ph.D. research in IRP labs as part of NIH’s Graduate Partnership Program presented their progress at that poster session and its virtual counterpart held February 15.
The two poster sessions made it clear that IRP graduate students are essential contributors to the life-changing discoveries made at NIH, from using geckos to learn about human eye diseases to investigating how the immune system combats infectious invaders to exploring ways to improve cancer treatment. Keep reading to learn about some of the bright scientists-in-training who showed off their work during the two-day event.
Findings Could Explain Why Caffeine Exposure In-Utero Increases Kids’ Risk for Obesity
Between books, the media, and well-meaning friends and relatives, new parents are inundated with advice about how to set their kids up for a happy and healthy future. However, what parents do before their children are even born can also have a huge impact on how they turn out. For instance, new IRP research suggests that a pregnant woman’s caffeine consumption can rewire her baby’s brain in ways that put the child at increased risk for obesity later in life.
IRP Study Points to the Biological Roots of Physical Activity’s Benefits
British science fiction writer Arthur C. Clarke once wrote that, “Any sufficiently advanced technology is indistinguishable from magic.” While not exactly a “technology,” exercise has such wide-ranging health benefits that it could understandably be mistaken for magic. Still, scientists persist in investigating precisely why physical activity is so good for us. Recently, a small IRP study showed that exercise training can help reduce the debilitating fatigue that often accompanies the autoimmune disease known as lupus, and also illuminated some of the underlying mechanisms that may lead to those benefits.
This page was last updated on Wednesday, March 15, 2023
