New Findings Could Help Improve Risk Assessment and Treatment
Tuesday, May 10, 2022
Fresh off celebrating Mother’s Day this past Sunday, as well as Women’s Health Week this week, it’s important to acknowledge that being a new mom isn’t easy. As joyful and exciting as a new baby might be, it can be exhausting and worrisome, too. Many new moms experience some level of baby blues, but for some women, those blues can take a downward turn into symptoms of more serious depression.
Approximately one out of every eight women in the U.S. experiences symptoms of postpartum depression, according to the U.S. Centers for Disease Control and Prevention. What’s more, a recent study led by IRP staff scientist Diane Putnick, Ph.D., has shown that the course of postpartum depression can differ significantly among women. The study of nearly 5,000 women not only showed that 25 percent of them experienced symptoms of postpartum depression, but it also found that depression symptoms followed several different patterns and could persist for at least three years after giving birth. Understanding these different patterns of symptoms and some of the risk factors associated with them may help physicians recognize and monitor mothers who are at higher risk for persistent depression.
IRP Scientists Keep it Short and Sweet in Competition’s Final Round
Wednesday, July 7, 2021
Science is so closely associated with long, jargon-laden lectures that scientists like Neil deGrasse Tyson and the IRP’s own Anthony Fauci have become celebrities for their ability to explain complex scientific concepts in a succinct and understandable way. On June 25, 17 postbacs, graduate students, and postdocs from across NIH showcased their own communication chops in the final round of the IRP’s annual Three-Minute Talks (TmT) competition.
IRP Study Could Help Identify Women at Greater Risk for Fertility Problems
Tuesday, February 2, 2021
As the calendar page turned from 2020 to 2021, many people adopted major lifestyle changes like healthier eating or significantly increasing their physical activity. While these New Year’s resolutions will likely improve their overall health, they could also wreak havoc on the reproductive cycles of a small set of women. New IRP research sheds light on the genetic factors that make some women susceptible to diet- or exercise-induced disruptions to their reproductive systems.
First-Trimester Blood Analysis Could Enable Earlier, More Effective Intervention
Tuesday, October 20, 2020
Imagine a world in which pregnant women routinely travel to places of healing and meet with wise sages who examine a bit of their blood to divine when their babies will be born. While this may sound like something out of Greek mythology, it may soon become a reality, as IRP researchers have developed a test that was able to use blood samples taken early in pregnancy to identify women who would later deliver their babies prematurely.
Smoking While Pregnant Affects a Woman’s Genes Differently From Her Baby’s
Tuesday, January 7, 2020
Decades of public health campaigns have made the health consequences of smoking common knowledge. However, for the few women who smoke while pregnant, the habit can affect not only their own bodies but also those of their unborn children. Intriguingly, according to a new study led by IRP researchers, so-called ‘epigenetic’ changes to DNA that can alter the behavior of genes differ significantly in smoking mothers compared to their babies, suggesting that maternal smoking may have unique, long-lasting effects on the way a child’s body functions.
Understanding Social and Behavioral Research in the IRP
Tuesday, December 3, 2019
The NIH IRP is world-renowned for its high-risk, high-reward biomedical research. While the NIH may be best known for its clinical and biomedical research on topics from cancer to allergies to addiction, IRP investigators have also produced a rich body of work conducted in the area of social and behavioral research (SBR). In this post, I will describe how SBR furthers the NIH’s goals of improving human health with some examples of the excellent work done by SBR investigators in the IRP.
New Insights Could Help Reduce Premature Births
Tuesday, May 28, 2019
Any baby born less than 37 weeks after conception is considered premature, but not all premature births have the same root cause. In a new study, IRP researchers have detailed how a particular component of the immune system can trigger premature labor, which could help doctors prevent more preterm births.
Tuesday, January 29, 2019
Virtually all parents would agree that having kids is a massive undertaking, and not just after they’re born. Many couples struggle to conceive, and each year thousands of American women experience complications when giving birth. With the help of the NIH’s state-of-the-art supercomputer, Biowulf, IRP senior investigator Rajeshwari Sundaram, Ph.D., develops and refines statistical tools that can guide prospective parents and their doctors through these challenges.
Monday, May 7, 2018
On Wednesday, May 2, hundreds of researchers gathered at NIH’s Natcher Conference Center to show off their recent discoveries. But unlike a typical scientific conference, the letters “M.D.” and “Ph.D.” were noticeably absent from these scientists’ credentials. Instead, the event — NIH’s annual Postbac Poster Day — celebrated the accomplishments of individuals participating in the NIH Postbaccalaureate Intramural Research Training Award (IRTA) Program.
Tuesday, April 24, 2018
In the midst of the 1957 Asian flu pandemic, doctors and researchers were understandably focused on treating patients and developing ways to contain the outbreak. It wasn’t until 30 years later that scientists began reporting that women who were pregnant when they caught the virus were more likely to have children who would later be diagnosed with schizophrenia.1 While that relationship remains controversial,2 numerous studies have since linked activation of a pregnant woman’s immune system with an increased risk that her child will develop certain psychiatric disorders, including not just schizophrenia but also autism spectrum disorder and major depressive disorder.3 A new IRP study has now expanded on this work by showing that exposure to higher levels of two immune system molecules in utero can noticeably alter the neurological and cognitive development of young children.4