environment

IRP’s Shannon Zenk Elected to the National Academy of Medicine

Nursing Research Leader Sheds Light on How Neighborhoods Influence Health

Dr. Shannon Zenk

When you think about public health, city planning might not be the first thing that comes to mind. Yet where we live — the quality of the buildings, the availability of places to walk and play safely, and the types of schools and stores in the neighborhood — can profoundly affect our health. This relationship has been emphasized by the COVID-19 pandemic, as close, stuffy living conditions, the need to take public transportation to essential jobs, and inequities in access to testing and vaccination sites all contributed to the larger reduction in life expectancy for Black and Latino Americans compared to Caucasians over the last two years.

Shannon N. Zenk, Ph.D., M.P.H., R.N., F.A.A.N., Director of the National Institute of Nursing Research (NINR), was elected to the National Academy of Medicine in 2021 for her research into how neighborhood characteristics affect the health of residents and contribute to the health disparities seen between communities with different racial and ethnic makeups and different levels of income.

Postdoc Profile: An Engineer Among Epidemiologists

Dr. Shuai Xie Brings a New Perspective to Research on Environmental Exposures

Dr. Shuai Xie

“Engineering is about solving problems,” says IRP postdoctoral fellow Shuai Xie, Ph.D., M.P.H.

Dr. Xie speaks from experience. One of the problems she was interested in solving during her graduate studies in chemical and environmental engineering was how to accurately measure the way airborne contaminants adhere to and release from indoor building materials. This is a particularly important problem to solve because those interactions can affect measurements of indoor air pollution, potentially rendering them inaccurate. Of course, Dr. Xie was not trying to solve this engineering problem for its own sake; accurately gauging contamination of indoor air is important for human health.

Rare Genetic Variants Underlie Susceptibility to Reproductive Disruption

IRP Study Could Help Identify Women at Greater Risk for Fertility Problems

pregnancy test

As the calendar page turned from 2020 to 2021, many people adopted major lifestyle changes like healthier eating or significantly increasing their physical activity. While these New Year’s resolutions will likely improve their overall health, they could also wreak havoc on the reproductive cycles of a small set of women. New IRP research sheds light on the genetic factors that make some women susceptible to diet- or exercise-induced disruptions to their reproductive systems.

Urban Upbringing Flips Genes’ Effects on Brain Activity

taxi cabs in a city street

It might seem easy to blame your parents for the way you turned out; after all, they raised you and gave you all of your DNA. But, before throwing blame around, consider saving some for the place where you grew up. According to new IRP research, being raised in an urban environment can dramatically alter how your genes influence your brain.1

Little Fish in a Big Pond Reveal New Answers to Old Questions

Dr. Eric Horstick in the lab

Studying the neural control of behavior is a challenge. Researchers must consider an animal’s environment, past experiences, and motivations. Work in relatively simple organisms, for example the invertebrate C. elegans, has teased apart the neural circuitry of highly stereotyped behaviors, like foraging. But in mammals, very little is known, “and that’s surprising given just how important behaviors like this are,” said Dr. Eric Horstick, who studies the molecular mechanisms underlying animal behavior.

Yasmine Belkaid Wins Sanofi–Institut Pasteur 2016 Award

Yasmine Belkaid

Yasmine Belkaid, chief of the Mucosal Immunology Section in the NIAID Laboratory of Parasitic Diseases, has won the Sanofi–Institut Pasteur 2016 International Mid-Career Award for “outstanding research in the life sciences…contributing to progress in global public health,” announced on December 13, 2016 in Paris.

Epigenetics in Cancer Individualizes Environmental and Hereditary Risks

You may already know that diet, obesity, exposure to the sun, radiation, and hormones are just a few of the many risk factors associated with cancer diagnoses. But, do you know about other risk factors, especially those playing out through epigenetics, the molecular relationship between the environment and our DNA? Read more...

It's Time for a Science FARE!

Speaking at the NIH Research Festival in September, Michael Gottesman, M.D., the NIH Deputy Director for Intramural Research said, “The real research is being done by the fellows, by the students.” The FARE awards are meant to commend those researchers doing outstanding work at the NIH.

FARE poster presenter at NIH Research Festival

Breaking the Chains Forged in Life

In Charles Dickens’ 1843 classic, A Christmas Carol, Ebenezer Scrooge is visited by four ghosts who help him to see the error of his ways and embrace a life of service. Scrooge is then able to correct the actions that could have led to his demise. Researchers studying epigenetics take on a similar task.

Marley's Ghost