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I am Intramural Blog

children

Unlocking the Genetic Mysteries of Rare Autoinflammatory Diseases

IRP Researcher Finds Explanations and Hope

Friday, February 28, 2025

child getting her cheek swabbed for DNA analysis

Rare Disease Day, celebrated on or near February 29 — the rarest day on the calendar — calls attention to the 300 million people in the world who have some sort of rare disease. For children born with one of those diseases, speedy diagnosis and treatment may be necessary to ward off long-term complications, but that’s much easier said than done. This is especially true for pediatric autoinflammatory diseases, in which the immune system attacks the child’s own body. IRP senior investigator Raphaela T. Goldbach-Mansky, M.D., M.H.S., has made it her mission to discover and define these diseases and the genes that cause them, and then find a way to provide treatment. 

Moms’ Microbes May Influence Babies’ Future Health

IRP Mouse Study Suggests Intervention Might Reduce Health Problems Associated with C-Section Births

Tuesday, October 15, 2024

mother holding her baby

Every kid’s first gift from their mom is half of her DNA, but nearly a third of children born nowadays miss out on a bonus present. That’s because babies born via vaginal delivery are exposed to the microorganisms that live in the vagina, but infants born via Cesarian section are not. A new IRP mouse study suggests that an intervention designed to make up for this missed opportunity could reduce the risk of certain health problems that are more common in babies born via C-section.

IRP Study Gets Kids Moving to Improve Blood Sugar Control

Interrupting Sedentary Time Could Help Stave Off Health Problems

Tuesday, April 18, 2023

little girl playing on a tablet

Many people don’t get much exercise these days, and kids are no exception. Whether at school, doing homework, or entertaining themselves online, children and teens spend hours on end sitting around. That lack of physical activity raises their risk for metabolic conditions like obesity and type 2 diabetes, but according to a recent IRP study, breaking up those long, sedentary periods with just a few minutes of exercise could yield noticeable benefits for their health.

Studying ADHD from Genes to the Brain Connectome

Tuesday, April 18, 2017

Contributed by an NIH clinical trial participant.

A magnetic resonance image (MRI) of a brain

My 8-year-old nephew Luke has a sixth-grade reading level, while still in the third grade. Yet, he often struggles to finish his chores. He carries a timer in his backpack to keep himself on task. His school provides Luke with special assistance, including extra time for tests and repeated, detailed instruction. The challenges arise because Luke, like his mother Rebecca, has attention-deficit/hyperactivity disorder (ADHD).

Isaac Fights to Inspire Others

Monday, April 10, 2017

Reblogged from The Children's Inn at NIH.

Isaac was born to fight. Arriving more than five weeks early by emergency C-section, it wasn’t just his way of coming into the world that made him different from his three brothers. While he initially looked healthy, his parents soon realized Isaac’s health was something he and the entire family would need to be fighting for every single day.

Faith, Hope, and Determination Help Teenager Fight a Rare Cancer

Monday, June 20, 2016

From The Children's Inn at NIH: Family Stories.

Terran (left) and her father, Terrence, at the Children's Inn at NIH

Terran Dupree, 16, is one of the most positive teenagers you will ever meet. With the brightest smile and the most humbling personality, you would never know that she is fighting a rare form of cancer.

New NIH Museum Acquisitions: Computer Boards to Coloring Books

Friday, April 15, 2016

NeuroPET Scanner Board

Have you ever had a PET scan? (That’s short for positron emission tomography.) This computer board, called a discriminator, was one of 64 in the Neuro-PET scanner designed and built at the NIH under the direction of Dr. Giovanni De Chiro.

Finding a Cure for Childhood Alzheimer’s – Johnathan’s Story

Thursday, February 11, 2016

Reblogged from The Children's Inn: Family Stories.

Searching for answers, Johnathan’s mother, Rebecca, and father, Keith, applied for their son to be considered as a participant in a clinical trial at the NIH National Institute of Child Health and Human Development (NICHD).

Jonathan at Nats game

Bugs, Recycling, and DNA—Oh My!

Wednesday, May 27, 2015

Most workplaces would never think of having hawks, turtles, beetles and stick bugs at an event for kids—but most workplaces are not the National Institutes of Health. Each year, the NIH Bethesda campus holds its Earth Day celebration in conjunction with Take Your Child to Work Day. Employees share their love of science with their kids while also learning about how to protect the environment.

Read more...

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