Dr. Joseph Goldberger and Pellagra: A Fearsome Disease Tamed
BY GORDON MARGOLIN, OFFICE OF NIH HISTORY AND STETTEN MUSEUM
To live in the American South in the early 1900s, you would have had to survive an uncontrolled epidemic known for its fatal consequences. The disease, pellagra, had been a worldwide scourge for about two centuries, with no known treatment. In 1914, Joseph Goldberger, an epidemiologist employed by the Hygienic Laboratory (forerunner of NIH), was assigned the task of determining the etiology of pellagra and hopefully finding a cure.
Meet your recently tenured colleagues: Sridhar Hannenhalli (NCI-CCR); Patricia Jensen (NIEHS); Lisa Mirabello (NCI-DCEG, pictured); John “Jay” Schneekloth Jr. (NCI-CCR); and Douglas R. Stewart (NCI-DCEG)
Congratulations to the four NIHers who are among the 100 new members recently elected to the National Academy of Medicine: Michael Lenardo (NIAID), Luigi D. Notarangelo (NIAID), Andre Nussenzweig (NCI), and Julie A. Segre (NHGRI).
ScPopCorn Gets to the Kernel of Single-Cell Experiments
BY TERESA PRZYTYCKA, NCBI
Researchers at the National Library of Medicine’s National Center for Biotechnology Information have created a new algorithm called scPopCorn (single-cell subpopulations comparison) to capture the differences among populations of cells from single-cell experiments.
Read about discoveries made by NIH intramural researchers: Improved gene therapy for sickle-cell disease; ALS gene may be a hitchhiker’s gene to the neuron; household bleach inactivates chronic wasting disease prions; how the brain can turn pain signals up or down; microbleeds may worsen outcome after head injury; and more.
Successful, resilient scientists need formal training in ethical decision-making as well as in the other aspects of the responsible conduct of research.
