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I am Intramural Blog

antiretroviral therapy

Study Identifies How Suppressed HIV Keeps Immune System on Edge

Findings Point to Approaches for Staving Off Health Problems in Infected Individuals

Tuesday, April 27, 2021

HIV-infected T cell

Over the four decades since it mysteriously began destroying the immune systems of Americans in New York and California, HIV has proven to be a frustratingly wily opponent for scientists. Even today, when treatments can fully suppress the virus in infected individuals, it continues to harm their health. A new IRP study has identified several ways dormant HIV might chronically stimulate the immune system, suggesting potential avenues for preventing the health problems that causes.

Simplifying HIV Treatment: A Surprising New Lead

Tuesday, November 15, 2016

Reblogged from the NIH Director's Blog.

CD4 cells in colon, SIV

The surprising results of an animal study are raising hopes for a far simpler treatment regimen for people infected with the AIDS-causing human immunodeficiency virus (HIV). Currently, HIV-infected individuals can live a near normal life span if, every day, they take a complex combination of drugs called antiretroviral therapy (ART). The bad news is if they stop ART, the small amounts of HIV that still lurk in their bodies can bounce back and infect key immune cells, called CD4 T cells, resulting in life-threatening suppression of their immune systems.

Toward an AIDS-Free Generation: Can Antibodies Help?

Thursday, January 28, 2016

Reblogged from the NIH Director's Blog.

VRC01 antibody binding to HIV

This year, an estimated 50,000 Americans will learn they have been newly infected with the human immunodeficiency virus (HIV), which causes AIDS. A new generation of safe, effective, and longer-lasting treatments to keep HIV in check is very much needed.

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