polio

A Long Tradition of Vaccine Breakthroughs

IRP Vaccine Research Stretches Back to the NIH’s Birth

Dr. Meyer (left) and Dr. Parkman (right), along with fellow NIAID scientist Hope Hopps, inspect a culture of the virus that causes rubella

Over the past few months, the world has gained a new appreciation for the long, difficult process of producing vaccines as it waits anxiously for one that will provide protection from the novel coronavirus. With the NIH Vaccine Research Center’s efforts to develop a COVID19 vaccine drawing a huge amount of media attention, it is easy to forget that the IRP has been making vital contributions to vaccine development for more than 100 years. These efforts have helped produce vaccinations for smallpox, rubella, hepatitis A, whooping cough, human papillomavirus (HPV), and several other diseases. Read on for a visual journey through the history of IRP vaccine research. 

Remembrances: Alexis Shelokov (1919–2016)

Alexis Shelokov

Alexis Shelokov, who studied the polio virus at the NIH in the 1950s and was a powerful scientific force in what would become the famed NIAID Laboratory of Infectious Diseases in Building 7, died on December 16, 2016, in Dallas, Texas. He had a prolific scientific career that took him around the world.

Early Vaccine Research: Rickettsial Diseases in 1951

Only one building was restricted during the 1951 NIH open house—Building 7, specially designed for infectious disease research. Children under 16 were not admitted. And there was only one demonstration: Dr. Karl Habel of NIH's National Institute of Allergy and Infectious Diseases (NIAID) showed the special procedures necessary in the collecting and handling of material for research on and vaccine development for rickettsial diseases carried by ticks. In this photo, is Dr. Habel following his own advice?

Karl Habel, NIH NIAID