health disparities

Medical Research Scholars Reflect on Their NIH Journeys

Future Physician-Scientists Spent a Year in IRP Labs

MRSP participant working in the lab

Many doctors not only treat patients directly, but also make valuable contributions to research that will improve medical care in the future. Each one of these talented ‘physician-scientists’ began his or her research career under the guidance of a more senior scientist. At the NIH, the Medical Research Scholars Program (MRSP) provides just such an experience to promising young medical students from all across the United States.

A Multi-Front Effort to Combat Coronavirus

IRP Research Examines Pandemic From All Angles

scientist working in the lab

The sheer number of labs and wide variety of scientific perspectives in the IRP make it particularly well-suited to combating a disease like COVID-19, which is affecting patients’ health and the world around them in a huge number of ways. IRP researchers specializing in psychology, genetics, epidemiology, and many other disciplines are pursuing an array of strategies to learn more about the novel coronavirus.

Facing Daytime Discrimination Linked to Sleep Struggles

IRP Study Examines Overlooked Contributor to Racial Health Disparities

African American woman sleeping

Recent news coverage of the deaths of George Floyd, Ahmaud Arbery, and Breonna Taylor, along with statistics reporting startlingly disproportionate death rates among black Americans infected with COVID-19, have made it clear that racial biases can be a matter of life and death. Meanwhile, it can be easy to overlook other, more subtle ways that discrimination can affect health, such as new IRP research that links instances of discrimination to poor sleep.

Postbac Poster Day Goes Virtual

Hundreds of Young Researchers Present Their Work Online

Amy Kwarteng

The COVID-19 pandemic has dramatically altered the way scientists are doing their work. Nevertheless, scientific research is a highly collaborative and interactive enterprise, so it remains essential for researchers to share and discuss their ideas and discoveries.

Every spring, the NIH’s Postbac Poster Day offers recent college graduates participating in the NIH’s Postbaccalaureate IRTA program the chance to show off the fruits of their labors and talk about their projects with both their fellow postbacs and the NIH’s many seasoned scientific veterans. Due to the need to maintain social distancing, the NIH's Office of Intramural Training and Education (OITE) went through considerable effort to move this year’s Postbac Poster Day to an online forum. The OITE staff's hard work paid off handsomely, with more than 870 postbacs presenting their research via WebEx on April 28, 29, and 30. Keep reading for a few examples of the fascinating scientific questions NIH’s latest crop of postbacs has been investigating.

The Social Side of Health

Understanding Social and Behavioral Research in the IRP

social and behavioral science diagram

The NIH IRP is world-renowned for its high-risk, high-reward biomedical research. While the NIH may be best known for its clinical and biomedical research on topics from cancer to allergies to addiction, IRP investigators have also produced a rich body of work conducted in the area of social and behavioral research (SBR). In this post, I will describe how SBR furthers the NIH’s goals of improving human health with some examples of the excellent work done by SBR investigators in the IRP.

Genes Contribute to Population-Based Differences in Antidepressant Response

5 Questions with Dr. Francis McMahon

doctor examining African American patient

Depression is one of the most common mental health conditions in the U.S., affecting nearly seven percent of American adults each year. With the increasing social and economic pressures of the modern world likely contributing to depressive symptoms, it is more important now than ever to study depression and the factors that contribute to recovery.

A number of variables contribute to an individual’s overall mental health and response to treatment, including elements of nature and nurture that have long been studied at the NIH. In a 2013 study, researchers led by IRP senior investigator Francis McMahon, M.D., set out to understand the complex genetic factors that he believed might help explain why antidepressants are less effective for African Americans with depression than for other populations. His research revealed that differences in socioeconomics and health explained most of those differences in antidepressant response, and the remaining differences were explained by differences in genetic ancestry, rather than self-reported race. The discovery that genetics play a role in this health disparity could help close the gap and improve depression treatment for African Americans.

Barbra Streisand Talks Up Women’s Heart Health

Barbra Streisand knows how to command an audience, whether she’s behind a microphone, a camera, or a podium. After a storied career beguiling theater-goers, Streisand’s new goal is not just to warm hearts but to save them from disease as well.

Barbra Streisand with NIH Director Francis Collins