brain

Untangling Alzheimer’s Disease — DNA Damage in Alzheimer’s

Drs. Hyundong Song and Yujun Hou, standing together here in their lab, are postdoctoral fellows working to find ways that doctors may one day effectively treat Alzheimer’s disease.

Given that Alzheimer’s is such a complex disease with many causes and pathways, it is not surprising that the search for effective treatments has proven difficult. So I spoke with Drs. Yujun Hou and Hyundong Song, postdoctoral fellows in the IRP’s Laboratory of Molecular Gerontology at the National Institute on Aging (NIA) to learn more about their approaches to meeting the challenge.

Exercise Releases Brain-Healthy Protein

Five images of different exercise activities

We all know that exercise is important for a strong and healthy body. Less appreciated is that exercise seems also to be important for a strong and healthy mind, boosting memory and learning, while possibly delaying age-related cognitive decline. How is this so? Researchers have assembled a growing body of evidence that suggests skeletal muscle cells secrete proteins and other factors into the blood during exercise that have a regenerative effect on the brain.

Fun with Science and Grownups at NIH

Bioinformatician Keri Richards shows 7-year-old James vials from a freezer in her lab at NIDCD. The vials contain DNA samples.

Hi, my name is James. I’ve always really liked science and I want to be a scientist when I grow up, but I never got to see where scientists work until I went to Take Your Child to Work Day at NIH with my Auntie Kit. It was awesome!

Sliding Through Science History, Part 2

Dietzgen Binary Slide Rule

Are you beginning to think that slide rules look alike? If you could see the types and number of scales, you’d understand that each slide rule model is different. There are specialized scales for cubes, spheres, voltage, etc. Check out a few of the slide rules that made history with IRP investigators.

Sliding Through Science History

Edwin Thacher slide rule

What do Isaac Newton, Thomas Jefferson, Albert Einstein, and Apollo astronauts have in common? They all used slide rules! We're highlighting some of the slide rules in our collection used by scientists at the NIH in their quest to improve human health.

Meet Children's Inn Resident Connor O’Brien

Connor, Childrens Inn at NIH

In the words of Connor: “A lot of times treatment for cancer and chronic diseases is very difficult to sustain. A lot of times it hurts. A lot of times you have to be given anesthesia, invasive things like that. The Inn gives you somewhere to come home to, somewhere to end your day, a place where you can have closure. Thank you all for making sure we have The Inn to come home to.”

New NIH Museum Acquisitions: Computer Boards to Coloring Books

NeuroPET Scanner Board

Have you ever had a PET scan? (That’s short for positron emission tomography.) This computer board, called a discriminator, was one of 64 in the Neuro-PET scanner designed and built at the NIH under the direction of Dr. Giovanni De Chiro.

Inside NIH’s Research Festival

As I trekked along the manicured sidewalk of Convent Drive, heading toward Building 10, I felt the now-familiar weight of the poster tube hanging over my shoulder. Inside that poster tube was, as the name implies, a scientific poster with which I was extremely familiar. My calves burned underneath the intensity of my power walk, as I remained calm and ready to present my project about mice undergoing anesthesia.

Lucy Bauer interviews Dr. Brenda Klaunberg of NIH Mouse Imaging Facility at ResearchFest