asthma

Digging Up the Roots of Food Allergies

IRP Research Aims to Explain the Perils of Peanuts and Other Foods

foods that can trigger food allergies, including shellfish, peanuts, and eggs

If you are a parent of school-age children, you’ve probably received a list of prohibited lunch foods and bans on birthday cupcakes. Going out to eat or cooking for guests can present a similar minefield of ingredients that many people must avoid. If it seems like food allergies are on the rise, it’s not your imagination. The U.S. Centers for Disease Control and Prevention (CDC) reports that the prevalence of food allergies has increased by 50 percent since the 1990s, making it a serious public health concern.

This May, Food Allergy Awareness Week reminds parents, kids, teachers, food service workers — really all of us — that we must remain vigilant to the risks of reactions to certain foods. These allergies affect nearly 32 million Americans, including 1 in 13 kids. If you think about the average classroom, that could be two or three children with severe allergies in one room. For many, even a tiny amount of an allergen can trigger a serious, even life-threatening response by the body’s immune system. To address this growing concern, IRP senior investigator Pamela A. Guerrerio, M.D., Ph.D., and her colleagues in the Food Allergy Research Section at the National Institute of Allergy and Infectious Diseases (NIAID) are working to unravel how genetics, immune system development, and environmental factors interact to cause food allergies in children.

Mapping the Pathway to an Asthma Attack

IRP Research Breathes New Life into Therapies for Treatment-Resistant Asthma

black man using an inhaler

It may start with a wheeze, a cough, or a feeling of tightness in the chest, but the result is the same. Acute asthma attacks make sufferers feel like they’re breathing through a straw while underwater. And even between attacks, having asthma can sometimes feel like your lungs are bound in tight bandages that make it difficult to take a deep breath.

World Asthma Day, observed this year on May 2, raises awareness of asthma, a common inflammatory disease that causes difficulty breathing in more than 260 million people worldwide, including 25 million in the U.S., roughly 8 percent of the country’s population. While many people can control their symptoms by taking medications and limiting certain activities, the condition still causes significant illness and even death.

A Hiatus From Food Could Benefit Asthma Patients

asthma inhaler

Between fast-food outlets, vending machines, and food trucks — not to mention good old-fashioned home cooking — many people face no shortage of opportunities to eat. But as satisfying as a crisp potato chip or a moist pork chop may be, people with asthma and many other conditions may prefer to resist tasty temptations if it means alleviating some of their symptoms. In a small pilot study, IRP researchers found evidence that abstaining from food for 24 hours could inhibit some of the cellular processes that cause asthmatics’ breathing problems.