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Highly talented scientists underlie the innovative biomedical research conducted at the NIH IRP. I asked one of them, Dr. Howard Young, Senior Investigator at the National Cancer Institute’s (NCI) Frederick, Maryland, campus, about how the environment of opportunity, access to resources, and proximity to cutting-edge science influences his work.
When I started this project, it was not my objective to develop a model for any specific disease, nor did I even suspect that the ultimate result would be some insight into autoimmune disease. The basic research question I was asking was why there are sequences in the 3’ untranslated region of the interferon-gamma mRNA that are more highly conserved than the coding region of the gene.