Drug Also Being Tested in Clinical Trials Against the New Coronavirus
BY BIJETA PRASAI, NHLBI
The drug remdesivir has antiviral effects against a variety of viruses including Middle East respiratory syndrome coronavirus (MERS-CoV) in rhesus monkeys, according to a study conducted by NIAID researchers at the Rocky Mountain Labs in Hamilton, Montana. Because MERS-CoV and the new COVID-19 coronavirus are closely related viruses, the scientists believe that remdesivir treatment will work against the new coronavirus as well. Clinical trials of remdesivir for COVID-19 are already underway
When COVID-19—a respiratory disease caused by the novel coronavirus severe acute respiratory syndrome coronavirus (SARS-CoV-2)—was first detected in December 2019 in Wuhan, Hubei Province, China, NIAID intramural and extramural scientists mobilized quickly to study the virus. Key areas of investigation include conducting basic research on its origins and how it causes disease, and developing animal study models, new treatments, and vaccines.
BY MICHAEL M. GOTTESMAN, DDIR, AND BRUCE TROMBERG, DIRECTOR, NIBIB
NIH’s Bioengineering Festival, which will be held this fall, recognizes the enormous potential of the NIH intramural research program to make innovative bioengineering contributions to biomedical research.
On March 3, 2020, President Donald Trump visited NIH for a tour of the Dale and Betty Bumpers Vaccine Research Center, which is overseen by the National Institute of Allergy and Infectious Diseases. Research is underway to develop a safe and effective vaccine for the novel coronavirus.
Part of the Next Generation of Clinical Researchers
BY LAURA STEPHENSON CARTER
Congratulations to the five investigators who recently joined the ranks of the Lasker Clinical Research Scholars Program, NIH’s collaborative effort with the Albert and Mary Lasker Foundation to nurture the next generation of clinical researchers: Sean Agbor-Enoh; Paule V. Joseph; Joanna Klubo-Gwiezdzinska; Nirali N. Shah; and David Takeda.
A Husband-Wife’s Quest to Cure a Genetic Prion Disease
BY SUNITA CHOPRA, NCI
Sonia Vallabh and her husband Eric Minikel hadn’t set out to build careers in science. But a tragic event changed their careers and they became patient-scientists in search of a cure for prion disease.
Shifts in White Blood-Cell Types Leading Up to a Breast-Cancer Diagnosis
BY MARLA BROADFOOT, NIEHS
Shifts in the populations of different types of leukocytes, or white-blood cells, in a woman’s bloodstream may signal a later diagnosis of breast cancer according to a study by researchers at the National Institute of Environmental Health Sciences.
Meet your recently tenured colleagues: J. Robert Hogg (NHLBI), Andrew D. Johnson (NHLBI), Vanja Lazarevic (NCI-CCR), Vijay Ramchandani (NIAAA), Sergio Damián Rosenzweig (CC, pictured), and S. Cenk Sahinalp (NCI-CCR).
Name this NIH luminary: She was an internationally recognized bacteriologist who worked at the NIH from 1936 until she retired in 1971. She was the first woman to head a laboratory at the NIH, becoming the chief of the Laboratory of Bacterial Products in 1958. And she stayed on as a guest worker for another 20 years after retiring, dying in 1995 at the age of 94.
Read about NIH scientific advances by intramural scientists: finding new ways to beat malaria; joint impact of exposure to toxic chemicals and stressful life events on preterm birth; persistant organic pollutants in maternal blood linked to smaller fetal size; and discovery of new autoinflammatory disease and its biological causes.
Palliative-care researchers Lori Wiener and Meaghann Weaver have written a children’s storybook—The Gift of Gerbert’s Feathers—to help families and caregivers of children with a terminal illness talk about progressive illness, engage children in decision making, and reduce the stigma surrounding the topic of death.
News about events, deadlines, lectures, and more. Note: In support of the Office of Personnel Management guidance to strengthen our efforts to protect the federal workforce and to ensure continuity of operations during the COVID-19 pandemic, most lectures and events are being held virtually or have been cancelled or postponed. Please check event details to determine status.