Advanced Imaging and Microscopy Facility Opens in Building 13
BY SUSAN CHACKO, CIT
The walls are freshly painted, new shelves have been installed, and the microscopes are being moved in. The sparkling new Advanced Imaging and Microscopy (AIM) facility in Building 13 on the NIH Bethesda campus is open for business. It’s a trans-NIH core facility that houses, operates, disseminates, and improves noncommercial, prototype optical-imaging systems.
Meet 11 more investigators who have become part of the Earl Stadtman Tenure-Track Investigator Program. The program, which was launched in 2009 and named for the legendary biochemist who worked at NIH for 50 years, is designed to recruit a diverse group of talented, early-career scientists pursuing interests across the biomedical-research spectrum. (Pictured: Sergio Ruiz Macias, NCI-CCR.)
The NIH intramural program has always been at the leading edge of developing new approaches to visualize biological phenomena, and some recent investments highlight our desire to remain at the cutting edge.
In 1984, the National Institute of Dental and Craniofacial Research (NIDCR) established a clinic to evaluate people with salivary dysfunction and to better understand and find more effective treatments. To mark the clinic’s 35th anniversary, NIDCR hosted a special grand rounds in November 2019 to trace the past, present, and future of research on the condition.
Technique key to scaling up manufacture of therapies from induced pluripotent stem cells
BY KATHRYN DEMOTT, NEI
Researchers from the National Eye Institute and the National Institute of Standards and Technology have used artificial intelligence (AI) to evaluate stem cell–derived “patches” of retinal pigment epithelium tissue for implanting into the eyes of patients with age-related macular degeneration, a leading cause of blindness.
Read about discoveries made by NIH intramural researchers: cerebral organoids provide clues on how to prevent virus-induced brain-cell death; mild side effects with single antidepressant dose of intravenous ketamine; promising drug combination against lethal childhood brain cancers; high amounts of screen time begin as early as infancy; permanent hair dye and straighteners may increase breast-cancer risk; vesicles released by bacteria may reduce the spread of HIV in human tissue; and more.
The Prescription for Acing an Interview Is Preparation and Practice
BY CRAIG MYRUM, NIA
A job interview might be the gateway to your success, but all too often, not enough time is spent preparing. Fortunately, you don’t need to look far to find the resources that will help you to ace your interview.
A microscopic image of a biopsied lymph node of a person with untreated HIV. NIH researchers found that in the setting of HIV-associated chronic immune activation, failure of HIV-specific B cells to enter or remain in the germinal centers may help explain the rarity of high-affinity protective antibodies.