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I am Intramural Blog

Swagata Basu

Swagata Basu is a postdoctoral fellow at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and is studying the role of Neuregulin-ErbB receptor signaling pathway in cortical excitability. She received her Ph.D. in neuroscience from the University of Texas at Dallas and used slice electrophysiology and cognition to understand the neural mechanisms underlying attention and impulsive behavior.

Posts by this author:

Unlocking Brain Function, One Neuron at a Time

Tuesday, March 17, 2015

The brain’s complexity and how its coordinated actions of billions of neurons shape our behavior and cognition have always fascinated me. So, I decided to go into neuroscience as a career and contribute to biomedical science.

Aspirations for Standards to Bolster Reproducibility in Scientific Research

Friday, March 13, 2015

Each day, hundreds of thousands of biomedical researchers around the world design and execute studies, with diverse trajectories and outcomes and where success is based largely on reproducibility. However, a large percentage of experiments using cell culture techniques have been labelled as irreproducible, with around 25 percent of all cell-line research described as either contaminated with other cells or mischaracterized in some way. In other words, if your kidney cancer cell isn’t really a kidney cancer line, then how will anyone else be able to reproduce your work?

From Mitochondria to Behavior

Monday, January 26, 2015

Mitochondria are dynamic cellular organelles involved in ATP synthesis and in apoptotic mechanisms (programmed cell death). However, in addition to these classically known functions, recent studies at the NIH have deciphered another intriguing role for mitochondria in the development and plasticity of neurons.

Let There Be Light!

Sunday, November 16, 2014

Optogenetics, a new technology used to control brain activity with light, has revolutionized the field of neuroscience in the past decade. The combination of two powerful tools, genetics and optics, has provided both temporal and spatial acuity in understanding how the brain works in response to sensory and motor cues in the environment. At the recent NIH Research Festival symposium titled “Optogenetic approaches to investigating the nervous system,” fellows and scientists from the NIH community presented their research encompassing topics that make use of this approach to study different systems.