Wednesday, August 29, 2012
Scientists have found that calorie restriction — a diet comprised of approximately 30 percent fewer calories but with the same nutrients of a standard diet — does not extend years of life or reduce age-related deaths in a 23-year study of rhesus monkeys. However, calorie restriction did extend certain aspects of health. The research, conducted by scientists at the National Institute on Aging (NIA) at the National Institutes of Health, is reported in the August 29, 2012 online issue of Nature.
Monday, August 27, 2012
Scientists have known for decades that cancer cells use more glucose than healthy cells, feeding the growth of some types of tumors. Now, a team that includes researchers from the National Institutes of Health's new National Center for Advancing Translational Sciences (NCATS) has identified compounds that delay the formation of tumors in mice, by targeting a key enzyme that governs how cancer cells use glucose and its metabolites.
Wednesday, August 22, 2012
For six months last year, a deadly outbreak of antibiotic-resistant bacteria kept infection-control specialists at the National Institutes of Health’s Clinical Center in a state of high alert. A New York City patient carrying a multi-drug resistant strain of Klebsiella pneumoniae, a microbe frequently associated with hospital-borne infections, introduced the dangerous bacteria into the 243-bed research hospital while participating in a clinical study in the summer of 2011.
Friday, August 3, 2012
Scientists have discovered a biological marker that may help to identify which depressed patients will respond to an experimental, rapid-acting antidepressant. The brain signal, detectable by noninvasive imaging, also holds clues to the agent’s underlying mechanism, which are vital for drug development, say National Institutes of Health researchers.
Wednesday, August 1, 2012
Researchers at the National Institutes of Health have found evidence that a unique type of immune cell contributes to multiple sclerosis (MS). Their discovery helps define the effects of one of the newest drugs under investigation for treating MS — daclizumab — and could lead to a new class of drugs for treating MS and other autoimmune disorders.
Wednesday, July 25, 2012
As they strive to develop new treatments for birth defects, or to prevent them, scientists at the National Institutes of Health have found a big ally in a small fish. An NIH video shows how the zebrafish, Danio rerio, is a valuable resource for scientists trying to understand the intricate process by which a fertilized egg develops into a fully formed individual, and the numerous diseases and conditions that can result when even a tiny part of the process goes wrong.
Monday, July 23, 2012
Distinct facial features not seen in many cases, NIH study finds
Most children exposed to high levels of alcohol in the womb do not develop the distinct facial features seen in fetal alcohol syndrome, but instead show signs of abnormal intellectual or behavioral development, according to a study by researchers at the National Institutes of Health and researchers in Chile.
Monday, July 23, 2012
Viral evolution and host protein levels predict rapid disease progression
Scientists at the National Institutes of Health have identified several factors in people infected with the hepatitis C virus that may predict whether the unusually rapid progression of disease from initial infection to severe liver conditions, such as cirrhosis, will occur. Knowing whether a patient's condition is likely to deteriorate quickly could help physicians decide on the best course of treatment.
Monday, July 16, 2012
A new study details how a suite of web-based tools provides the research community with greatly improved capacity to compare data derived from large collections of genomic information against thousands of drugs.
Thursday, July 12, 2012
Catherine Bushnell, Ph.D., an internationally recognized pain and neuroscience researcher, has been appointed scientific director of a new research program focusing on the role of the brain in perceiving, modifying, and managing pain. Based in the National Center for Complementary and Alternative Medicine (NCCAM), part of the National Institutes of Health, this collaborative effort will complement basic science and clinical research efforts of other ongoing intramural neuroscience, imaging, and mental and behavioral health research programs.