The Organ Prophet

Hannah Valantine Can Predict Heart-Transplant Rejection Before It Happens

It was a chance encounter with a falling apple that inspired Sir Isaac Newton to develop his theory of gravity. A chance encounter inspired NIH cardiologist Hannah Valantine, too. But her encounter wasn’t with a piece of fruit. It was with a 2008 research paper published in the Proceedings of the National Academy of Sciences U.S.A. that inspired a theory about a new way to detect the rejection of transplanted hearts.

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Defending the Honor of the Y Chromosome

2015 Nirenberg Lecture with David Page

“Sex differences in incidence and severity are not the exception—they are in fact the rule,” said Whitehead Institute Director David Page at the 2015 Nirenberg Lecture held at NIH in May. “For every affected man, there are two or three women affected with rheumatoid arthritis. Flip it around and take autism spectrum disorders—for every girl diagnosed with an autism spectrum disorder, [there are] about five or six boys diagnosed.”

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Colleagues: Recently Tenured

Meet your recently tenured colleagues, several of whom have leadership positions in other institutes: Philip Bourne (NLM-NCBI and OD), pictured; George Koob (NIDA and NIAAA); Xiaoling Li (NIEHS); Jon Lorsch (NICHD and NIGMS); Hannah Valantine (NHLBI and OD). 

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New Methods

“Voicing My Choices”: Terminally Ill Teens and Young Adults Express Their Wishes

More than 11,000 adolescents and young adults (15 to 34 years old) die each year from cancer and other terminal illnesses. But they usually are not involved in planning their own end-of-life care. Decisions are often left up to grief-stricken parents who have no idea what their children want. And the adolescents and young adults are afraid of hurting their parents, so they may refrain from expressing their wishes.

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Photographic Moment

From Biospecimens to Hard Hats

The team of Diane Poole (NCI) and Amanda Vandeveer (NCI) won first and second places in the fourth annual “In-Focus Safe Workplaces for All” photography contest. First place honored their photo depicting a scientist making a careful inventory of biospecimens (shown); second place went to their photograph of a crew of workers demonstrating hard-hat safety. Dale Lewis (NCI) took third place with his photo of a fireman wearing safety gear.

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Research Briefs

NIH research highlights: zebrafish role in accelerating the discovery of disease genes in humans; appetite-regulating neural pathway identified; alcohol-use disorder on the rise; potential biomarker for predicting treatment response in vasculitis patients, unraveling the mystery of the tubulin code (shown); and potential treatment for melanoma.

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News You Can Use


There’s Much You Can Do

You may know that federal workers are allowed to have personal social-media accounts. But you may not realize that activities associated with your personal account have to comply with certain guidelines. Here's what you need to know.

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News Briefs

Building 4 was dedicated recently to honor  former U.S. Senator Lowell Weicker Jr.; Alan Alda of M*A*S*H fame uses improvisational theater games to coach scientists on how to become better at communicating about their work.

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The Training Page


2015 Career Symposium

There is no such thing as an “alternative career,” a term that is sometimes applied in a derogatory way to any career outside of academia, Office of Intramural Training and Education (OITE) Director Sharon Milgram reminded the audience that had gathered for the eighth annual NIH Career Symposium on May 15.

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The SIG Beat


Read about three new SIGs—Extracellular Vesicles, Hispanic Health Research, and Inflammatory Disease—and the Natural Products SIG’s summary of lecture by German researcher Ruth Brack-Werner (pictured) on natural products as weapons against lethal viruses.

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Lectures, workshops, and more.

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