anemia

IRP’s Cynthia Dunbar Elected to National Academy of Medicine

Studies of Blood Stem Cells Stimulate Pioneering Therapeutic Approaches

Dr. Cynthia Dunbar

The National Academy of Medicine (NAM), first established in 1970 by the National Academy of Sciences as the Institute of Medicine (IOM), is comprised of more than 2,000 elected members from around the world who provide scientific and policy guidance on important matters relating to human health. Election to the NAM is considered one of the highest honors in the fields of health and medicine and recognizes individuals who have not only made critical scientific discoveries but have also demonstrated a laudable commitment to public service.

IRP Distinguished Investigator Cynthia E. Dunbar, M.D., was elected to the NAM last year for her pioneering research into hematopoietic stem cells, the cells in bone marrow that develop into oxygen-carrying red blood cells, infection-fighting white blood cells, and clot-forming platelets. Her work has led to valuable insights into the production of those blood cells, called hematopoiesis, and its role in human health. Her discoveries have also resulted in new approaches to treat disease by improving stem cell functioning or manipulating stem cells with gene therapy.

Folic Acid: Learning About B Vitamins

An example of preventive medicine added to the 1951 NIH Clinical Center time capsule was a vial of synthetic folic acid, a B vitamin. Folic acid had first been isolated in crystalline form in 1943, but in 1951, Dr. James Hundley wrote that the “exact chemical form in which folic acid exists as a functional unit in metabolism is still in doubt."

lab technicians monitor changes in rats’ weight and blood for folic acid deficiency