Research advances from the National Institutes of Health (NIH) Intramural Research Program (IRP) often make headlines. Read the news releases that describe our most recent findings:
Whether you’re shedding pounds with the help of effective new medicines, slimming down after weight loss surgery or cutting calories and adding exercise, there will come a day when the numbers on the scale stop going down, and you hit the dreaded weight loss plateau.
In a recent study, Kevin Hall, a researcher at the National Institutes of Health who specializes in measuring metabolism and weight change, looked at when weight loss typically stops depending on the method people were using todrop pounds. He broke down the plateau into mathematical models using data from high-quality clinical trials of different ways to lose weight to understand why people stop losing when they do. The study published Monday in the journal Obesity.
A candidate dengue vaccine developed by scientists at the National Institutes of Health has been found to be safe and to stimulate a strong immune response in most vaccine recipients, according to results from an early-stage clinical trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH. The trial results appeared in the January 17 issue of the Journal of Infectious Diseases.
NIH researcher assists in study of Norwegian women
Norwegian pregnant women who received a vaccine against the 2009 H1N1 influenza virus showed no increased risk of pregnancy loss, while pregnant women who experienced influenza during pregnancy had an increased risk of miscarriages and still births, a study has found. The study suggests that influenza infection may increase the risk of fetal loss.
NIH researcher assists in study of Norwegian women
Norwegian pregnant women who received a vaccine against the 2009 H1N1 influenza virus showed no increased risk of pregnancy loss, while pregnant women who experienced influenza during pregnancy had an increased risk of miscarriages and still births, a study has found. The study suggests that influenza infection may increase the risk of fetal loss.
The National Institute on Minority Health and Health Disparities (NIMHD) of the National Institutes of Health announced today that Eddie Reed, M.D., an award-winning physician and internationally recognized cancer researcher, will serve as the clinical director for the NIMHD Intramural Research Program.
Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health, and the University of Oxford, U.K., have shed light on a long-standing enigma about the structure of a protein related to the Hepatitis B virus. Their findings were reported in Structure.
Mouse study findings may offer clues for understanding cell fusion
Researchers at the National Institutes of Health have identified proteins that allow muscle cells in mice to form from the fusion of the early stage cells that give rise to the muscle cells.
NIH researchers identify new gene variants associated with risk for complex inflammatory syndrome
Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. For nearly 2,000 years, traders used this 4,000-mile network linking the Far East with Europe to exchange goods, culture and, in the case of the Silk Road disease, genes. National Institutes of Health researchers and their Turkish and Japanese collaborators published their findings in the Jan. 6, 2013, advance online issue of Nature Genetics.
Scientists have discovered a gene that interferes with the clearance of hepatitis C virus infection. They also identified an inherited variant within this gene, Interferon Lambda 4 (IFNL4), that predicts how people respond to treatment for hepatitis C infection. The results of this study, by investigators at the National Cancer Institute (NCI), part of the NIH, and their collaborators at NIH and other institutions, were published online in Nature Genetics on Jan. 6, 2013.
Working-age adults with disabilities account for a disproportionately high amount of annual emergency department visitors, reports a comparison study from National Institutes of Health researchers. As emergency department care may not be the best to address non-urgent concerns and is higher in cost, finding a way to decrease these visits is of interest to many stakeholders.
Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many pancreatic and prostate tumors, according to research at the National Institutes of Health.
