Research advances from the National Institutes of Health (NIH) Intramural Research Program (IRP) often make headlines. Read the news releases that describe our most recent findings:
Whether you’re shedding pounds with the help of effective new medicines, slimming down after weight loss surgery or cutting calories and adding exercise, there will come a day when the numbers on the scale stop going down, and you hit the dreaded weight loss plateau.
In a recent study, Kevin Hall, a researcher at the National Institutes of Health who specializes in measuring metabolism and weight change, looked at when weight loss typically stops depending on the method people were using todrop pounds. He broke down the plateau into mathematical models using data from high-quality clinical trials of different ways to lose weight to understand why people stop losing when they do. The study published Monday in the journal Obesity.
Increased live birth rate in subgroup of participants
A daily low dose of aspirin does not appear to prevent subsequent pregnancy loss among women with a history of one or two prior pregnancy losses, according to researchers at the National Institutes of Health.
Obesity, rather than diet, causes changes in the colon that may lead to colorectal cancer, according to a study in mice by the National Institutes of Health. The finding bolsters the recommendation that calorie control and frequent exercise are not only key to a healthy lifestyle, but a strategy to lower the risk for colon cancer, the second leading cause of cancer-related death in the United States.
State of the art research facility on NIH campus will foster new collaborations among scientists studying the brain
The National Institutes of Health will host a scientific symposium and a dedication ceremony March 31- April 1, 2014, to celebrate the completion of the John Edward Porter Neuroscience Research Center. This state of the art facility brings together neuroscientists from 10 institutes and centers across the NIH in an effort to spur new advances in our understanding of the nervous system in health and disease.
Symptom management, practical concerns are focus of topic
A new Web resource from the National Institutes of Health is aimed at helping people address a sensitive subject—the end of life. The latest addition to NIHSeniorHealth, the health and wellness website for older adults, the End of Life module provides visitors with information about the most common issues faced by the dying and their caregivers.
Ten projects that will enable non-government researchers to conduct clinical research at the National Institutes of Health’s Clinical Center in Bethesda, Md. were announced today. Through these three-year, renewable awards of up to $500,000 per year, scientists from institutions across the United States will collaborate with government scientists in a highly specialized hospital setting. The NIH Clinical Center is the largest hospital in the nation devoted entirely to clinical research.
NIH intramural-led study uncovers biology behind improper graft remodeling, points to treatment strategies
National Institutes of Health researchers have identified a biological pathway that contributes to the high rate of vein graft failure following bypass surgery. Using mouse models of bypass surgery, they showed that excess signaling via the Transforming Growth Factor Beta (TGF-Beta) family causes the inner walls of the vein become too thick, slowing down or sometimes even blocking the blood flow that the graft was intended to restore. Inhibition of the TGF-B signaling pathway reduced overgrowth in the grafted veins.
Hundreds of middle school students from the Washington, D.C., area will visit the National Museum of Health and Medicine in Silver Spring, Md., this week for a special brain-bending experience. Alongside scientists from seven institutes of the National Institutes of Health, these students will become neuroscientists for a day as part of the 14th annual Brain Awareness Week celebration at the museum.
NIH study of couples implicates three common phthalates in delay
Women whose male partners have high concentrations of three common forms of phthalates, chemicals found in a wide range of consumer products, take longer to become pregnant than women in couples in which the male does not have high concentrations of the chemicals, according to researchers at the National Institutes of Health and other institutions.
In the largest, most comprehensive, nationwide study to examine the prevalence of allergies from early childhood to old age, scientists from the National Institutes of Health report that allergy prevalence is the same across different regions of the United States, except in children 5 years and younger.
Mutation in related gene found in patient with Carney Complex
Mutations in a gene containing part of the information needed to make an enzyme that provides energy for governing basic cell functions appear to contribute to a severe form of Cushing’s syndrome, according to researchers at the National Institutes of Health and nine European research institutions.
