Research advances from the National Institutes of Health (NIH) Intramural Research Program (IRP) often make headlines. Read the news releases that describe our most recent findings:
Saxophonist Joey Berkley was living his dream: he was playing jazz in New York City. But about 20 years ago, he noticed his left hand wasn’t cooperating. It got worse and worse.
“As soon as I picked my horn up and touched — literally just touched my horn — my hands would twist into pretzel shapes,” Berkley recalled in a conversation with Morning Edition host A Martinez.
Berkley was experiencing focal dystonia, a movement disorder marked by involuntary muscle contractions.
He said he “muscled through it” as best he could. But that meant he wasn’t just pressing down on the keys of his sax — he was crushing them. “My fingers would literally be bleeding afterwards,” he said. “I had to quit playing.”
Joey Berkley learned of an experimental procedure at the National Institutes of Health in Bethesda, Maryland, that involved placing an electrode directly into his brain.
Researchers have a new weapon in their arsenal to diagnose and treat traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) among military service members and civilians. The National Institutes of Health Clinical Center began imaging patients last week on a first-of-its-kind, whole-body simultaneous positron emission topography (PET) and magnetic resonance imaging (MRI) device. The Biograph mMR offers a more complete picture of abnormal metabolic activity in a shorter time frame than separate MRI and PET scans, two tests many patients undergo.
A study supported by the U.S. Department of Health and Human Services could not validate or confirm previous research findings that suggested the presence of one of several viruses in blood samples of people living with chronic fatigue syndrome. The new study also could not find the viruses in blood samples of healthy donors who were previously known to not have the viruses.
Hospitalizations for alcohol and drug overdoses — alone or in combination — increased dramatically among 18- to 24-year-olds between 1999 and 2008, according to a study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health.
Investigators have identified a new class of human immune cells that behave like stem cells. These cells, a subtype of T lymphocytes, which comprise a small fraction of white blood cells, may prove more effective than any previously reported type of T cell for treating tumors. The study, by scientists at the National Cancer Institute (NCI), part of the National Institute of Health, describes how these stem cell-like T cells can trigger a prolonged immune attack against tumor cells by continuously generating killer T cells and regenerating themselves. The findings were published online Sept. 18, 2011, in Nature Medicine.
In one of the largest genomics studies ever, an international research consortium that includes the National Institutes of Health has identified 29 genetic variations across 28 regions of the human genome that influence blood pressure. This unprecedented effort brought together more than 230 researchers across six continents and scanned the genomes of over 200,000 people. The results will appear in the Sept. 11 edition of Nature.
The NIH Clinical Center, the clinical research hospital at the National Institutes of Health in Bethesda, Md., is the 2011 recipient of the Lasker~Bloomberg Public Service Award. The award will be presented in ceremonies on Sept. 23 by the Albert and Mary Lasker Foundation, which has recognized outstanding advances in medical research each year since 1945, in New York City. The award honors the Clinical Center for serving as a model institution that has transformed scientific advances into innovative therapies and provided high-quality care to patients.
Two doses of the human papillomavirus (HPV) vaccine Cervarix were as effective as the current standard three-dose regimen after four years of follow-up, according to researchers from the National Cancer Institute (NCI), part of the National Institutes of Health, and their colleagues. The results of the study, based on data from a community-based clinical trial of Cervarix in Costa Rica, appeared online Sept.9, 2011, in the Journal of the National Cancer Institute.
Gene therapy plus an injection of copper dramatically improved survival in mice with a condition that mimics the often fatal childhood disorder Menkes disease, according to a study by researchers at the National Institutes of Health.
A new Medical Research Scholars Program for medical and dental students will begin in September 2012 in Bethesda, Md., the National Institutes of Health has announced. The program will offer research experiences with intramural investigators from across NIH in basic science laboratories, and in clinical and translational research conducted at the NIH Clinical Center, the world's largest hospital dedicated to patient-oriented research.
Researchers at the National Institutes of Health have created a mathematical model—and an accompanying online weight simulation tool—of what happens when people of varying weights, diets and exercise habits try to change their weight. The findings challenge the commonly held belief that eating 3,500 fewer calories—or burning them off exercising—will always result in a pound of weight loss.