Taking the random out of biopsy sampling

2011

Challenge

Biopsy is currently the only way to confirm a diagnosis of prostate cancer. However, despite improvements in technology, prostate biopsy sampling remains a challenge, and cancerous lesions may be missed. Novel diagnostic tools are needed to ensure more accurate biopsies and better cancer detection rates.

Advance

IRP researchers Peter L. Choyke, M.D., Peter A. Pinto, M.D., Bradford Wood, M.D., and colleagues developed a combined magnetic resonance imaging (MRI) and ultrasound-guided prostate biopsy, a minimally invasive technique that allows for the detection of cancer at a far higher rate than current biopsy techniques.

Impact

Fusion MRI/ultrasound-guided biopsy has been shown in clinical trials to detect more instances of cancer than standard biopsies, consequently leading to more accurate diagnosis and more appropriate course of treatment for cancer patients.

Publications

Turkbey B, Xu S, Kruecker J, Locklin J, Pang Y, Shah V, Bernardo M, Baccala A, Rastinehad A, Benjamin C, Merino MJ, Wood BJ, Choyke PL, Pinto PA. (2011). Documenting the location of systematic transrectal ultrasound-guided prostate biopsies: correlation with multi-parametric MRI. Cancer Imaging. 11, 31-6.