In the News

Research advances from the National Institutes of Health (NIH) Intramural Research Program (IRP) often make headlines. Read the news releases that describe our most recent findings:

Compound improves health, increases lifespan of obese mice

Researchers have reported that obese male mice treated with a synthetic compound called SRT1720 were healthier and lived longer compared to non-treated obese mice. The experimental compound was found to improve the function of the liver, pancreas and heart in mice.

Cigarette smoking implicated in half of bladder cancers in women

Current cigarette smokers have a higher risk of bladder cancer than previously reported, and the risk in women is now comparable to that in men, according to a study by scientists from the National Cancer Institute (NCI), part of the National Institutes of Health. The report was published on Aug. 16, 2011, in the Journal of the American Medical Association.

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Scientists show how gene variant linked to ADHD could operate

A study using mice provides insight into how a specific receptor subtype in the brain could play a role in increasing a person’s risk for attention-deficit hyperactivity disorder (ADHD). The research, conducted by the Intramural Research Program (IRP) at the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, could also help explain how stimulants work to treat symptoms of ADHD.

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NIH-Led Team Maps Route for Eliciting HIV Neutralizing Antibodies

Researchers have traced in detail how certain powerful HIV neutralizing antibodies evolve, a finding that generates vital clues to guide the design of a preventive HIV vaccine, according to a study appearing in Science Express this week. The discoveries were made by a team led by the Vaccine Research Center (VRC) at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

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NIH appoints Director of Intramural Center for Regenerative Medicine

National Institutes of Health Director Francis S. Collins, M.D., Ph.D., has announced the appointment of Mahendra S. Rao, M.D., Ph.D. as the director for the new NIH Intramural Center for Regenerative Medicine (NIH-CRM). The NIH-CRM is an initiative to create a world-class center of excellence in stem cell technology on the NIH campus, including induced pluripotent stem cells (iPSC), which can have applications in many systems and organs of the body. This is an initiative of the NIH Common Fund and will be administered by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

Standard aplastic anemia therapy improves patient outcomes better than newer version

A comparison clinical study of two aplastic anemia treatments found that ATGAM, currently the only licensed aplastic anemia drug in the United States, improved blood cell counts and survival significantly more than Thymoglobulin, a similar but reportedly more potent treatment. The research was carried out by the National Heart, Lung and Blood Institute (NHLBI), part of the National Institutes of Health.

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NIH researchers identify gene variant in Proteus syndrome

A team of researchers has identified the genetic mutation that causes Proteus syndrome, a rare disorder in which tissue and bone grows massively out of proportion. The discovery, which has implications for potential drug therapies and even cancer, appears in the July 27, 2011, early online edition of the New England Journal of Medicine. The team was led by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health.

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NIH investigators discover new mechanism that may be important for learning and memory

New findings in mice suggest that the timing when the neurotransmitter acetylcholine is released in the brain’s hippocampus may play a key role in regulating the strength of nerve cell connections, called synapses. Understanding the complex nature of neuronal signaling at synapses could lead to better understanding of learning and memory, and novel treatments for relevant disorders, such as Alzheimer’s disease and schizophrenia.

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This page was last updated on Wednesday, May 11, 2022