William E. Paul Lecture: Gaining New Insights into ‘Fundamental Immunology’ Using Imaging and Computation

Wednesday, October 19, 2022, 2:00 to 3:00pm

NIH Clinical Center (Building 10), Lipsett Amphitheater

This year's William E. Paul Lecture, part of NIH’s Wednesday Afternoon Lecture Series (WALS), will be presented by IRP Distinguished Investigator Ronald Germain, M.D., Ph.D. Dr. Germain leads the Lymphocyte Biology Section (LBS) at the National Institute of Allergy and Infectious Diseases (NIAID), where his team has made numerous contributions to the understanding of the cell biology of antigen processing and presentation by MHC class I and especially class II molecules. It also has examined recognition of these ligands by T cells with a focus on the signaling mechanisms involved in ligand discrimination. Recently, the LBS has developed novel, highly multiplex section and volume imaging methods (Histo-cytometry and Ce3D) that allow an unprecedented analysis of cell phenotype, signaling, function, and location in complex tissue settings.

This lecture can also be viewed on NIH Videocast.