Warren Casey, Ph.D., D.A.B.T.

Senior Scientist

Division of Translational Toxicology


530 Davis Drive (Keystone Bldg)
530 Davis Dr
Durham, NC 27713



Research Topics

Casey, Ph.D., D.A.B.T., is responsible for identifying strategic opportunities, recruiting key partners, securing funding, and managing collaborative programs that support the mission of DTT and NIEHS. His primary areas of focus are:

  • Working with federal partners to utilize human serum and tissue repositories to better understand the connection between environmental exposures, genotypes, and disease.
  • Identifying and evaluating new technologies that facilitate the self-collection of biospecimens, along with the development of analytical technologies for examining these samples.
  • Promoting interagency and international initiatives to develop more accurate human-centric methods for the toxicological testing of drugs and chemicals.


Warren Casey, Ph.D., D.A.B.T., earned his Bachelor of Science in Biochemistry and a Ph.D. in Microbiology from North Carolina State University (NCSU). Following his academic pursuits, he joined GlaxoSmithKline, where he spent 15 years in various roles, including preclinical biomarker discovery and investigative toxicology. Since 2007, he has been recognized as a Diplomat of the American Board of Toxicology. Throughout his career, he has assumed several significant leadership roles. These include being the Executive Director of the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), Director of the NTP Interagency Center for the Evaluation of Toxicological Methods, and the Acting Chief of Predictive Toxicology and Biomolecular Screening Branches within the Division of Translational Toxicology (DTT). Currently, he is the Director of Strategic Partnerships at the DTT. In addition to his scientific career achievements, he was a Captain in the U.S. Army and participated in Operation Desert Shield/Storm in Saudi Arabia from 1990-1992., receiving the National Defense Service Medal and Southwest Asia Service Medal for combat operations in Operation Desert Storm.

Selected Publications

  1. Bell SM, Phillips J, Sedykh A, Tandon A, Sprankle C, Morefield SQ, Shapiro A, Allen D, Shah R, Maull EA, Casey WM, Kleinstreuer NC. An Integrated Chemical Environment to Support 21st-Century Toxicology. Environ Health Perspect. 2017;125(5):054501.
  2. Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W. Integrated decision strategies for skin sensitization hazard. J Appl Toxicol. 2016;36(9):1150-62.
  3. Felter SP, Bhat VS, Botham PA, Bussard DA, Casey W, Hayes AW, Hilton GM, Magurany KA, Sauer UG, Ohanian EV. Assessing chemical carcinogenicity: hazard identification, classification, and risk assessment. Insight from a Toxicology Forum state-of-the-science workshop. Crit Rev Toxicol. 2021;51(8):653-694.
  4. Sullivan K, Allen DG, Clippinger AJ, Wilson DM, Edwards SW, Glover K, Mansouri K, Settivari R, Wijeyesakere SJ, Casey W. Mind the gaps: Prioritizing activities to meet regulatory needs for acute systemic lethality. ALTEX. 2021;38(2):327-335.
  5. Parish ST, Aschner M, Casey W, Corvaro M, Embry MR, Fitzpatrick S, Kidd D, Kleinstreuer NC, Lima BS, Settivari RS, Wolf DC, Yamazaki D, Boobis A. An evaluation framework for new approach methodologies (NAMs) for human health safety assessment. Regul Toxicol Pharmacol. 2020;112:104592.

Related Scientific Focus Areas

This page was last updated on Wednesday, February 14, 2024