Robert Sills, D.V.M., Ph.D.

Senior Scientist

Comparative and Molecular Pathogenesis Branch

NIEHS

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B332
David P Rall Building
111 Tw Alexander Dr
Research Triangle Park, NC 27709

984-287-3839

sills@niehs.nih.gov

Research Topics

Robert C. Sills, D.V.M., Ph.D., DACVP, Fellow IATP, is a senior staff scientist/pathologist and Chief of the Cellular and Molecular Pathology Branch (CMPB) in the Division of Translational Toxicology (DTT) at the National Institute of Environmental Health Sciences (NIEHS). He oversees 6 groups that are responsible for Anatomical and Clinical Toxicologic Pathology Evaluations, Molecular Pathology Investigations, Laboratory Animal Medicine, and Core Pathology Laboratories (Pathology Support, Special Techniques) in the National Toxicology Program (NTP) and NIEHS.

Additionally, he is an adjunct professor in the Department of Toxicology at the University of North Carolina School of Medicine at Chapel Hill, North Carolina, and in the Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University.

His research interests include the study of molecular mechanisms of non-cancer and cancer diseases related to environmental exposures. Of special interest is in the area of neuropathology evaluations. He is a member of the American College of Veterinary Pathologists (ACVP), Society of Toxicologic Pathology (STP), and the American Veterinary Medical Association (AVMA). He presently serves on the Executive Council for the Society of Toxicologic Pathology and is the associate editor for the environmental pathobiology section of Veterinary Pathology.

Biography

Sills received his Doctor of Veterinary Medicine degree from Tuskegee University (1984) and completed an internship in anatomical pathology from Tuskegee University (1985) and a combined residency/Ph.D. in toxicologic pathology from Michigan State University (1991). He is a diplomate of the American College of Veterinary Pathologists.

Sills has served as the President of the Society of Toxicologic Pathology (2013-2014). He chaired STP annual meeting sessions on the human genome, implications for toxicologic pathology and carcinogenesis, and a session on cellular and molecular neurocarcinogenesis, and toxicologic pathology of the nervous system. Also, he co-chaired the International Life Sciences Institute (ILSI) seminar series on current issues in neuropathology.

Selected Publications

  1. Bolon B, Garman RH, Pardo ID, Jensen K, Sills RC, Roulois A, Radovsky A, Bradley A, Andrews-Jones L, Butt M, Gumprecht L. STP position paper: Recommended practices for sampling and processing the nervous system (brain, spinal cord, nerve, and eye) during nonclinical general toxicity studies. Toxicol Pathol. 2013;41(7):1028-48.
  2. Kaufmann W, Bolon B, Bradley A, Butt M, Czasch S, Garman RH, George C, Gröters S, Krinke G, Little P, McKay J, Narama I, Rao D, Shibutani M, Sills R. Proliferative and nonproliferative lesions of the rat and mouse central and peripheral nervous systems. Toxicol Pathol. 2012;40(4 Suppl):87S-157S.
  3. Hoenerhoff MJ, Pandiri AR, Snyder SA, Hong HH, Ton TV, Peddada S, Shockley K, Witt K, Chan P, Rider C, Kooistra L, Nyska A, Sills RC. Hepatocellular carcinomas in B6C3F1 mice treated with Ginkgo biloba extract for two years differ from spontaneous liver tumors in cancer gene mutations and genomic pathways. Toxicol Pathol. 2013;41(6):826-41.
  4. Pandiri AR, Sills RC, Ziglioli V, Ton TV, Hong HH, Lahousse SA, Gerrish KE, Auerbach SS, Shockley KR, Bushel PR, Peddada SD, Hoenerhoff MJ. Differential transcriptomic analysis of spontaneous lung tumors in B6C3F1 mice: comparison to human non-small cell lung cancer. Toxicol Pathol. 2012;40(8):1141-59.

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This page was last updated on Monday, July 22, 2024