Lothar George Hennighausen, Ph.D.

Senior Investigator

Genetics and Physiology Section, Laboratory of Cell & Molecular Biology

NIDDK

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Building NIHBC 08, Room 101
8 Center Dr
Bethesda, MD 20892

+1 301 328 6183

lotharh@mail.nih.gov

Research Topics

Our ultimate goal is to unlock the genetic logic that controls the mammary genome and leads to a functional mammary gland during pregnancy.

Biography

  • Technical University, Munich, Germany, Hans-Fischer Senior Fellow (2020 – present)
  • FASEB Conference on Prolactin, Keynote Speaker (2019)
  • Sookmyung University, Seoul, South Korea, Brain Korea 21+, Visiting Professor (2018-present)
  • Student invited Seminar Speaker Series, Case Western Reserve University, (2018)
  • Mammary Gland Biology Gordon Conference, Keynote Speaker (2016)
  • Chonnam National University Medical School, Hwasun, South Korea, Visiting Professor (2016-present)
  • Annual Meeting, Cytokine Society, San Francisco, Plenary Speaker (2013)
  • Distinguished Lecture Series, Lady Davis Institute, McGill, Montreal, Speaker (2012)
  • Graduate Research Symposium, Memorial University, St. John’s, Canada, Keynote Speaker (2011)
  • Endocrine Society, Annual meeting, San Diego, Plenary Speaker (2010)
  • Korean Society for Molecular and Cellular Biology, Annual Meeting, Plenary Speaker, Seoul, Republic of Korea (2009)
  • Member and Chair (2009-2014), Scientific Advisory Board, Georg-Speyer Haus, Frankfurt, Germany (2009-present)
  • Chonnam National University, Gwangju, Visiting Professor (2008-2011)
  • Korean Society of Science and Engineering, Distinguished World Class Scholar (2008)
  • Deutsche Forschungsgemeinschaft, Mercator Professorship (2007)
  • Keystone Symposia, Whistler, Canada Plenary Speaker (2004)
  • Alexander von Humboldt Foundation, Humboldt Fellow (1992)
  • Selected, National Press Club, Mammary Gland Bioreactor, Washington D.C. (1987)
  • Deutsche Forschungsgemeinschaft, Post-Doctoral Fellowship (1983)
  • EMBO, Short-term Research Fellowship at Edinburgh University (1980)
  • Studienstiftung des Deutschen Volkes, Graduate Student Fellowship (1978)
  • Ph.D., University of Cologne, 1982
  • M.S., University of Cologne, 1979
  • B.S., Philipp University of Marburg, 1977

Selected Publications

  1. Lee HK, Knabl L, Moliva JI, Knabl L Sr, Werner AP, Boyoglu-Barnum S, Kapferer S, Pateter B, Walter M, Sullivan NJ, Furth PA, Hennighausen L. mRNA vaccination in octogenarians 15 and 20 months after recovery from COVID-19 elicits robust immune and antibody responses that include Omicron. Cell Rep. 2022;39(2):110680.
  2. Lee HK, Knabl L, Walter M, Knabl L Sr, Dai Y, Füßl M, Caf Y, Jeller C, Knabl P, Obermoser M, Baurecht C, Kaiser N, Zabernigg A, Wurdinger GM, Furth PA, Hennighausen L. Prior Vaccination Exceeds Prior Infection in Eliciting Innate and Humoral Immune Responses in Omicron Infected Outpatients. Front Immunol. 2022;13:916686.
  3. Lee HK, Willi M, Miller SM, Kim S, Liu C, Liu DR, Hennighausen L. Targeting fidelity of adenine and cytosine base editors in mouse embryos. Nat Commun. 2018;9(1):4804.
  4. Shin HY, Wang C, Lee HK, Yoo KH, Zeng X, Kuhns T, Yang CM, Mohr T, Liu C, Hennighausen L. CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome. Nat Commun. 2017;8:15464.
  5. Shin HY, Willi M, HyunYoo K, Zeng X, Wang C, Metser G, Hennighausen L. Hierarchy within the mammary STAT5-driven Wap super-enhancer. Nat Genet. 2016;48(8):904-911.

Related Scientific Focus Areas

This page was last updated on Friday, February 10, 2023