Lenore Joy Launer, Ph.D.

Senior Investigator

Laboratory of Epidemiology and Population Science


Gateway Building, Room 3C309
7201 Wisconsin Avenue
Bethesda, MD 20814



Research Topics

Studies in the Neuroepidemiology Section focus on understanding the contribution of genetic, inflammatory, metabolic, vascular, and hormonal factors to sub-clinical and clinical outcomes in brain disease and investigating the links between brain disease and other common diseases of old age. Research is conducted using large epidemiologic studies, which allow us to test in the general population, hypotheses on risk/protective factors and mechanisms identified at a more basic science level.


Dr. Launer received her Ph.D. in epidemiology and nutrition from Cornell University. From 1990 to 1999 she held academic appointments in the Netherlands (Erasmus University Medical School, Free University, National Institute for Public Health) where she collaborated in many epidemiologic studies of neurologic diseases including dementia and migraine headache. Dr. Launer joined NIA as Head of the Neuroepidemiology Unit in February 1999 and received tenure in 2005.

Selected Publications

  1. Sabayan B, van Buchem MA, Sigurdsson S, Zhang Q, Harris TB, Gudnason V, Arai AE, Launer LJ. Cardiac hemodynamics are linked with structural and functional features of brain aging: the age, gene/environment susceptibility (AGES)-Reykjavik Study. J Am Heart Assoc. 2015;4(1):e001294.

  2. Palm-Meinders IH, Koppen H, Terwindt GM, Launer LJ, Konishi J, Moonen JM, Bakkers JT, Hofman PA, van Lew B, Middelkoop HA, van Buchem MA, Ferrari MD, Kruit MC. Structural brain changes in migraine. JAMA. 2012;308(18):1889-97.

  3. 19th Workshop of the International Stroke Genetics Consortium, April 28-29, 2016, Boston, Massachusetts, USA: 2016.001 MRI-defined cerebrovascular genomics-The CHARGE consortium. Neurol Genet. 2017;3(1 Suppl 1):S2-S11.

  4. Ding J, Sigurðsson S, Jónsson PV, Eiriksdottir G, Charidimou A, Lopez OL, van Buchem MA, Guðnason V, Launer LJ. Large Perivascular Spaces Visible on Magnetic Resonance Imaging, Cerebral Small Vessel Disease Progression, and Risk of Dementia: The Age, Gene/Environment Susceptibility-Reykjavik Study. JAMA Neurol. 2017;74(9):1105-1112.

  5. Gelber RP, Launer LJ, White LR. The Honolulu-Asia Aging Study: epidemiologic and neuropathologic research on cognitive impairment. Curr Alzheimer Res. 2012;9(6):664-72.

This page was last updated on August 22nd, 2018