Kyle Messier, Ph.D.

Stadtman Investigator

National Toxicology Program/Spatiotemporal Health Analytics Group


2008 530 Davis Drive (Keystone Bldg)
530 Davis Dr
Durham, NC 27713


Research Topics

Spatiotemporal models are a class of statistical models that explicitly account for the spatial and/or temporal correlation in data. They have a rich history in fields such mining, forestry, petroleum engineering , exposure science, and most recently, machine learning and artificial intelligence. Within environmental health sciences, there is an ever-growing need for methodological development and applications of spatiotemporal models that can handle the large, complex data and interdisciplinary challenges. Towards this end, the central theme of the Spatiotemporal Health Analytics Group (SHAG) is to develop spatiotemporal methods and applications in environmental and human health exposure science while also exploring innovative applications of geospatial and spatiotemporal methods in toxicology.

Currently, the Spatiotemporal Health Analytics Group is interested in:

  • Geospatial exposure, disparity, and risk mapping
  • Geospatial mapping of mixture exposure through common molecular initiating events
  • Spatiotemporal mapping connections to toxicology
  • Toxicokinetic and toxicological-based geospatial risk mapping


Kyle P. Messier, Ph.D. Messier is a Stadtman Tenure-Track Investigator in the Division of the National Toxicology Program (DNTP). He also holds a joint appointment with the National Institute of Minority Health and Health Disparities (NIMHD) in Bethesda, Maryland. Messier received a B.S. in Environmental Studies from the University of North Carolina at Asheville and a M.S. and Ph.D. from the University of North Carolina at Chapel Hill. He also holds a secondary appointment in the NIEHS Biostatistics and Computational Biology Branch.

Selected Publications

  1. Messier KP, Katzfuss M. Scalable penalized spatiotemporal land-use regression for ground-level nitrogen dioxide. Ann Appl Stat. 2021;15(2):688-710.
  2. Messier KP, Tidwell LG, Ghetu CC, Rohlman D, Scott RP, Bramer LM, Dixon HM, Waters KM, Anderson KA. Indoor versus Outdoor Air Quality during Wildfires. Environ Sci Technol Lett. 2019;6(12):696-701.
  3. Chambliss SE, Pinon CPR, Messier KP, LaFranchi B, Upperman CR, Lunden MM, Robinson AL, Marshall JD, Apte JS. Local- and regional-scale racial and ethnic disparities in air pollution determined by long-term mobile monitoring. Proc Natl Acad Sci U S A. 2021;118(37).

Related Scientific Focus Areas

This page was last updated on Thursday, June 9, 2022