Jill Koshiol, Ph.D

Stadtman Investigator

Infections and Immunoepidemiology Branch

NCI/DCEG

9609 Medical Center Drive
Room SG/6E212
Rockville, MD 20850

240-276-7178

koshiolj@mail.nih.gov

Research Topics

In addition to her continued interest in investigating the epidemiology of infectious agents and cancer, Dr. Koshiol is increasingly interested in the role of immune stimulation and inflammation in carcinogenesis. Infection elicits inflammatory and other immune responses. Measuring infection and immune and inflammatory responses in biological specimens can provide novel insights into carcinogenesis, identify molecular subtypes of cancer, and identify potential associations with cancer outcomes.

Given her interest in immune response and carcinogenesis, Dr. Koshiol has recently focused her research program on hepatobiliary cancers, which are linked to both infections and inflammation. Dr. Koshiol is the Principal Investigator for the Shanghai Biliary Tract Cancer Study and leads the Chile Gallbladder Cancer Pilot Study. Using these studies and others, she plans to evaluate the role of immune response and inflammation in hepatobiliary cancers to elucidate etiologic mechanisms and aid cancer prevention through the identification of cancer-related molecular pathways and targets.

Biography

Dr. Jill Koshiol received her Ph.D. in epidemiology from the University of North Carolina at Chapel Hill School of Public Health in 2005. Subsequently, she joined the Genetic Epidemiology Branch of the Division of Cancer Epidemiology and Genetics as a Cancer Prevention Fellow. There, she focused on the role of human papillomavirus (HPV) in upper gastrointestinal and lung cancer, as well as infection- and immune-related conditions in lung and hematopoietic cancers. Dr. Koshiol joined the Infections and Immunoepidemiology Branch as a Research Fellow in 2008 and became an Earl Stadtman Tenure-Track Investigator in 2010.

Selected Publications

  1. Nogueira L, Foerster C, Groopman J, Egner P, Koshiol J, Ferreccio C, Gallbladder Cancer Chile Working Group.. Association of aflatoxin with gallbladder cancer in Chile. JAMA. 2015;313(20):2075-7.

  2. Koshiol J, Pawlish K, Goodman MT, McGlynn KA, Engels EA. Risk of hepatobiliary cancer after solid organ transplant in the United States. Clin Gastroenterol Hepatol. 2014;12(9):1541-9.e3.

  3. Nogueira L, Freedman ND, Engels EA, Warren JL, Castro F, Koshiol J. Gallstones, cholecystectomy, and risk of digestive system cancers. Am J Epidemiol. 2014;179(6):731-9.

  4. Koshiol J, Lam TK, Gridley G, Check D, Brown LM, Landgren O. Racial differences in chronic immune stimulatory conditions and risk of non-Hodgkin's lymphoma in veterans from the United States. J Clin Oncol. 2011;29(4):378-85.

  5. Royer RH, Koshiol J, Giambarresi TR, Vasquez LG, Pfeiffer RM, McMaster ML. Differential characteristics of Waldenström macroglobulinemia according to patterns of familial aggregation. Blood. 2010;115(22):4464-71.


This page was last updated on April 29th, 2016