In addition to providing structural information, MRI has the potential to non-invasively map physiologic parameters and function. Our research focuses on optimally exploiting this potential by investigating the mechanisms behind MRI contrast, exploring avenues to manipulate the contrast, and optimizing MRI data acquisition and analysis to achieve optimum sensitivity, resolution, reliability, and accuracy. Specific aims are the development of MRI techniques for the measurements of structural anatomy, tissue metabolism, tissue perfusion, and the spatial distribution of brain activity. Recent work has focused on high field MRI technology, the magnetic properties of brain tissue, and the study of spontaneous brain activity.
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- Picchioni D, Özbay PS, Mandelkow H, de Zwart JA, Wang Y, van Gelderen P, Duyn JH. Autonomic arousals contribute to brain fluid pulsations during sleep. Neuroimage. 2022;249:118888.
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- van Gelderen P, Li X, de Zwart JA, Beck ES, Okar SV, Huang Y, Lai K, Sulam J, van Zijl PCM, Reich DS, Duyn JH, Liu J. Effect of motion, cortical orientation and spatial resolution on quantitative imaging of cortical R(2)* and magnetic susceptibility at 0.3 mm in-plane resolution at 7 T. Neuroimage. 2023;270:119992.
Related Scientific Focus Areas
Biomedical Engineering and Biophysics
This page was last updated on Friday, August 25, 2023