Jeff H. Duyn, Ph.D.
Advanced MRI Section
Building 10, Room B1D724
10 Center Drive
Bethesda, MD 20814
In addition to providing structural information, MRI has the potential to non-invasively map physiologic parameters and function. Our research focuses on optimally exploiting this potential by investigating the mechanisms behind MRI contrast, exploring avenues to manipulate the contrast, and optimizing MRI data acquisition and analysis to achieve optimum sensitivity, resolution, reliability, and accuracy. Specific aims are the development of MRI techniques for the measurements of structural anatomy, tissue metabolism, tissue perfusion, and the spatial distribution of brain activity. Recent work has focused on high field MRI technology, the magnetic properties of brain tissue, and the study of spontaneous brain activity.
Chang C, Leopold DA, Schölvinck ML, Mandelkow H, Picchioni D, Liu X, Ye FQ, Turchi JN, Duyn JH. Tracking brain arousal fluctuations with fMRI. Proc Natl Acad Sci U S A. 2016;113(16):4518-23.
van Gelderen P, Jiang X, Duyn JH. Rapid measurement of brain macromolecular proton fraction with transient saturation transfer MRI. Magn Reson Med. 2017;77(6):2174-2185.
Gudino N, Duan Q, de Zwart JA, Murphy-Boesch J, Dodd SJ, Merkle H, van Gelderen P, Duyn JH. Optically controlled switch-mode current-source amplifiers for on-coil implementation in high-field parallel transmission. Magn Reson Med. 2016;76(1):340-9.
Liu X, Yanagawa T, Leopold DA, Fujii N, Duyn JH. Robust Long-Range Coordination of Spontaneous Neural Activity in Waking, Sleep and Anesthesia. Cereb Cortex. 2015;25(9):2929-38.
Liu X, de Zwart JA, Schölvinck ML, Chang C, Ye FQ, Leopold DA, Duyn JH. Subcortical evidence for a contribution of arousal to fMRI studies of brain activity. Nat Commun. 2018;9(1):395.
Related Scientific Focus Areas
Biomedical Engineering and Biophysics
This page was last updated on September 12th, 2018