Ivan Ovcharenko, Ph.D.

The Ovcharenko Research Group focuses on developing artificial intelligence (AI) methods for the functional characterization of noncoding DNA in the human genome. The group leverages advanced AI approaches deployed in cloud computing environments to accurately identify disease-causing variants associated with a range of complex human diseases and disorders, including type 2 diabetes, Parkinson's disease, Alzheimer's disease, polycystic ovary syndrome (PCOS), glaucoma, and others.

In addition, the group investigates silencers and super-silencers and their roles in carcinogenesis and metastatic cancer progression. This research spans multiple cancer types, including diffuse large B-cell lymphoma (DLBCL), ovarian cancer, and breast cancer.

Dr. Ovcharenko is a Senior Investigator in the Division of Intramural Research at the National Library of Medicine (NLM), National Institutes of Health (NIH). He joined NIH as a tenure-track investigator in 2007, following his tenure at Lawrence Livermore National Laboratory (2003-2007) and a visiting scientist appointment at the Joint Genome Institute. Previously, he served as a Staff Scientist at Lawrence Berkeley National Laboratory (2001-2003) and completed a postdoctoral fellowship at the University of California, Berkeley (1999-2001).

Dr. Ovcharenko serves on the editorial boards of several scientific journals and has authored more than 90 publications, including papers in Science, Nature, and Proceedings of the National Academy of Sciences (PNAS), primarily in the field of regulatory genomics.