Dr. Wistow received his BA in Biochemistry from Oxford University, UK in 1976 and his Ph.D. in Protein X-ray crystallography from the University of London, UK in 1982. His thesis work described the first three-dimensional structure of a γ-crystallin. He joined NEI in 1982 and became a Section Chief in 1989. Dr. Wistow received NEI Director’s Awards in 1991 and 2000, an NEI Appreciation award in 2005 and an NIH Director’s Award in 2001. In 1997 he received the Cogan Award of the Association for Research in Vision and Ophthalmology "In recognition of outstanding and promising research on the structure and function of the lens".
- Sagar V, Wistow G. Acquired Disorder and Asymmetry in a Domain-Swapped Model for γ-Crystallin Aggregation. J Mol Biol. 2022;434(9):167559.
- Fan J, Rajapakse D, Peterson K, Lerner J, Parsa S, Ponduri A, Sagar V, Duncan T, Dong L, Wistow G. Retbindin mediates light-damage in mouse retina while its absence leads to premature retinal aging. Exp Eye Res. 2021;209:108698.
- Rajapakse D, Peterson K, Mishra S, Fan J, Lerner J, Campos M, Wistow G. Amelotin is expressed in retinal pigment epithelium and localizes to hydroxyapatite deposits in dry age-related macular degeneration. Transl Res. 2020;219:45-62.
- Rajapakse D, Peterson K, Mishra S, Wistow G. Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. Exp Cell Res. 2017;361(2):333-341.
- Sagar V, Chaturvedi SK, Schuck P, Wistow G. Crystal Structure of Chicken γS-Crystallin Reveals Lattice Contacts with Implications for Function in the Lens and the Evolution of the βγ-Crystallins. Structure. 2017;25(7):1068-1078.e2.
Related Scientific Focus Areas
Genetics and Genomics
Molecular Biology and Biochemistry
This page was last updated on Wednesday, August 9, 2023