Dima A. Hammoud, M.D.
Center for Infectious Disease Imaging (CIDI)
NIH Clinical Center
Building 10, Room 1C368
10 Center Drive
Bethesda, MD 20892
The Hammoud lab focuses on the development of preclinical, translational, and clinical molecular imaging applications to improve the understanding of the pathophysiology of infection and to provide reliable imaging biomarkers of infectious diseases. Current research in the laboratory focuses on understanding the pathophysiology of HIV in the brain and periphery, and on the development and validation of novel fungal infection-specific imaging biomarkers in animal models and patients, using non-invasive molecular imaging techniques, mainly positron emission tomography (PET). Another interest of the lab is molecular imaging of high-consequence viral infections such as Ebola, Nipah and Lassa viruses, in collaboration with the NIAID Integrated Research Facility (IRF), a biosafety level (BSL)-2 to BSL-4 biomedical research facility based in Fort Detrick, Maryland.
Dr. Hammoud is senior investigator and deputy director of the Center for Infectious Disease Imaging (CIDI), a joint initiative between Radiology and Imaging Sciences (RIS) at the NIH Clinical Center and the National Institute of Allergy and Infectious Diseases (NIAID). Dr. Hammoud earned an MD degree at the American University of Beirut in Lebanon. After her diagnostic radiology residency, she completed two fellowships and then joined the Neuroradiology faculty at Johns Hopkins School of Medicine as Assistant Professor. In 2006, she joined the Neuroradiology faculty at NIH. Dr Hammoud is board-certified in diagnostic imaging by the American Board of Radiology, and has completed fellowships in neuroradiology and PET imaging. She currently serves as member of the intramural NIH PET Steering Committee member, the Molecular Imaging Subcommittee of the Scientific Program Committee (SPC) at RSNA, the Leadership Committee at the "Women In Molecular Imaging Network" (WIMIN), WMIS and as co-chair of the "Imaging of Infections interest group" (IOI), WMIS.
Lai J, Shah S, Knight R, Martinez-Orengo N, Patel R, Mitchell A, Wang Z, Basuli F, Ordonez AA, Jain SK, Hammoud DA. Evaluation of 2-[18F]-Fluorodeoxysorbitol PET Imaging in Preclinical Models of Aspergillus Infection. J Fungi (Basel). 2021;8(1).
Shah S, Sinharay S, Patel R, Solomon J, Lee JH, Schreiber-Stainthorp W, Basuli F, Zhang X, Hagen KR, Reeder R, Wakim P, Huzella LM, Maric D, Johnson RF, Hammoud DA. PET imaging of TSPO expression in immune cells can assess organ-level pathophysiology in high-consequence viral infections. Proc Natl Acad Sci U S A. 2022;119(15):e2110846119.
Schreiber-Stainthorp W, Solomon J, Lee JH, Castro M, Shah S, Martinez-Orengo N, Reeder R, Maric D, Gross R, Qin J, Hagen KR, Johnson RF, Hammoud DA. Longitudinal in vivo imaging of acute neuropathology in a monkey model of Ebola virus infection. Nat Commun. 2021;12(1):2855.
Wang Z, Manion MM, Laidlaw E, Rupert A, Lau CY, Smith BR, Nath A, Sereti I, Hammoud DA. Redistribution of brain glucose metabolism in people with HIV after antiretroviral therapy initiation. AIDS. 2021;35(8):1209-1219.
Riggle BA, Sinharay S, Schreiber-Stainthorp W, Munasinghe JP, Maric D, Prchalova E, Slusher BS, Powell JD, Miller LH, Pierce SK, Hammoud DA. MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice. Proc Natl Acad Sci U S A. 2018;115(51):E12024-E12033.
Related Scientific Focus Areas
Microbiology and Infectious Diseases
This page was last updated on May 24th, 2022