Dima A. Hammoud, M.D.

Senior Investigator

Center for Infectious Disease Imaging (CIDI)

NIH Clinical Center

Building 10, Room 1C368
10 Center Drive
Bethesda, MD 20892

301-402-3041

hammoudd@mail.nih.gov

Research Topics

The Hammoud lab focuses on the development of preclinical, translational, and clinical molecular imaging applications to improve the understanding of the pathophysiology of infection and to provide reliable imaging biomarkers of infectious diseases. Current research in the laboratory focuses on understanding the pathophysiology of HIV in the brain and periphery, and on the development and validation of novel fungal infection-specific imaging biomarkers in animal models and patients, using non-invasive molecular imaging techniques, mainly positron emission tomography (PET). Another interest of the lab is molecular imaging of high-consequence viral infections such as Ebola, Nipah and Lassa viruses, in collaboration with the NIAID Integrated Research Facility (IRF), a biosafety level (BSL)-2 to BSL-4 biomedical research facility based in Fort Detrick, Maryland.

Biography

Dr. Hammoud is senior investigator and deputy director of the Center for Infectious Disease Imaging (CIDI), a joint initiative between Radiology and Imaging Sciences (RIS) at the NIH Clinical Center and the National Institute of Allergy and Infectious Diseases (NIAID). Dr. Hammoud earned an MD degree at the American University of Beirut in Lebanon. After her diagnostic radiology residency, she completed two fellowships and then joined the Neuroradiology faculty at Johns Hopkins School of Medicine as Assistant Professor. In 2006, she joined the Neuroradiology faculty at NIH. Dr Hammoud is board-certified in diagnostic imaging by the American Board of Radiology, and has completed fellowships in neuroradiology and PET imaging. She currently serves as member of the intramural NIH PET Steering Committee member, the Molecular Imaging Subcommittee of the Scientific Program Committee (SPC) at RSNA, the Leadership Committee at the "Women In Molecular Imaging Network" (WIMIN), WMIS and as co-chair of the "Imaging of Infections interest group" (IOI), WMIS.

Selected Publications

  1. Shah S, Sinharay S, Matsuda K, Schreiber-Stainthorp W, Muthusamy S, Lee D, Wakim P, Hirsch V, Nath A, Mascio MD, Hammoud DA. Potential Mechanism for HIV-Associated Depression: Upregulation of Serotonin Transporters in SIV-Infected Macaques Detected by 11C-DASB PET. Front Psychiatry. 2019;10:362.

  2. Hammoud DA, Sinharay S, Shah S, Schreiber-Stainthorp W, Maric D, Muthusamy S, Lee DE, Lee CA, Basuli F, Reid WC, Wakim P, Matsuda K, Hirsch V, Nath A, Di Mascio M. Neuroinflammatory Changes in Relation to Cerebrospinal Fluid Viral Load in Simian Immunodeficiency Virus Encephalitis. MBio. 2019;10(3).

  3. Riggle BA, Sinharay S, Schreiber-Stainthorp W, Munasinghe JP, Maric D, Prchalova E, Slusher BS, Powell JD, Miller LH, Pierce SK, Hammoud DA. MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice. Proc Natl Acad Sci U S A. 2018;115(51):E12024-E12033.

  4. Hammoud DA, Boulougoura A, Papadakis GZ, Wang J, Dodd LE, Rupert A, Higgins J, Roby G, Metzger D, Laidlaw E, Mican JM, Pau A, Lage S, Wong CS, Lisco A, Manion M, Sheikh V, Millo C, Sereti I. Increased Metabolic Activity on 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography in Human Immunodeficiency Virus-Associated Immune Reconstitution Inflammatory Syndrome. Clin Infect Dis. 2019;68(2):229-238.

  5. Hammoud DA, Sinharay S, Steinbach S, Wakim PG, Geannopoulos K, Traino K, Dey AK, Tramont E, Rapoport SI, Snow J, Mehta NN, Smith BR, Nath A. Global and regional brain hypometabolism on FDG-PET in treated HIV-infected individuals. Neurology. 2018;91(17):e1591-e1601.


This page was last updated on August 20th, 2020