Dima A. Hammoud, M.D.

Senior Investigator

Center for Infectious Disease Imaging (CIDI)

NIH Clinical Center

Building 10, Room 1C368
10 Center Drive
Bethesda, MD 20892

301-402-3041

hammoudd@mail.nih.gov

Research Topics

The Hammoud lab focuses on the development of preclinical, translational, and clinical molecular imaging applications to improve the understanding of the pathophysiology of infection and to provide reliable imaging biomarkers of infectious diseases.

Current research in the laboratory focuses on the development and validation of novel fungal-specific imaging biomarkers in animal models of infection which can then be translated to human applications, using non-invasive molecular imaging techniques, mainly positron emission tomography (PET).

Another interest of the lab is utilizing molecular imaging to better understand the pathophysiology of HIV in the brain and periphery, and to identify HIV reservoirs.

Dr. Hammoud also collaborates with the NIAID Integrated Research Facility (IRF), a biosafety level (BSL)-2 to BSL-4 biomedical research facility based in Fort Detrick, Maryland to image high-consequence viral infections such as Ebola, Nipah and Lassa viruses.

Biography

Dr. Hammoud is senior investigator and deputy director of the Center for Infectious Disease Imaging (CIDI), a joint initiative between Radiology and Imaging Sciences (RIS) at the NIH Clinical Center and the National Institute of Allergy and Infectious Diseases (NIAID). Dr. Hammoud earned an MD degree at the American University of Beirut in Lebanon. After her diagnostic radiology residency, she completed two fellowships, joined the Neuroradiology faculty at Johns Hopkins School of Medicine as Assistant Professor, before finally joining the Neuroradiology faculty at NIH-CC.

Dr. Hammoud is board-certified in diagnostic imaging by the American Board of Radiology and has completed fellowships in neuroradiology and PET imaging. She currently serves as chair of the "Imaging of Infections interest group" (IOI) at the World Molecular Imaging Society (WMIS), Chair of the animal care and use committee (ACUC) at the NIH-CC, as a committee member of the intramural PET Steering Committee at NIH and since 2021, as a member of the scientific program committee of the World Molecular imaging Congress (WMIC). She previously served as Leadership Committee Member at the Women In Molecular Imaging Network (WIMIN) at WMIS, Vice-Chair of Neurosciences (Brain imaging council) at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) and Board Member of SNMMI CMIIT Center of Excellence (COE) Program Task Force.

Selected Publications

  1. Shah S, Lai J, Basuli F, Martinez-Orengo N, Patel R, Turner ML, Wang B, Shi ZD, Sourabh S, Peiravi M, Lyndaker A, Liu S, Seyedmousavi S, Williamson PR, Swenson RE, Hammoud DA. Development and preclinical validation of 2-deoxy 2-[(18)F]fluorocellobiose as an Aspergillus-specific PET tracer. Sci Transl Med. 2024;16(760):eadl5934.
  2. Lai J, Shah S, Martinez-Orengo N, Knight R, Alemu E, Turner ML, Wang B, Lyndaker A, Shi J, Basuli F, Hammoud DA. PET imaging of Aspergillus infection using Zirconium-89 labeled anti-β-glucan antibody fragments. Eur J Nucl Med Mol Imaging. 2024.
  3. Shah S, Sinharay S, Patel R, Solomon J, Lee JH, Schreiber-Stainthorp W, Basuli F, Zhang X, Hagen KR, Reeder R, Wakim P, Huzella LM, Maric D, Johnson RF, Hammoud DA. PET imaging of TSPO expression in immune cells can assess organ-level pathophysiology in high-consequence viral infections. Proc Natl Acad Sci U S A. 2022;119(15):e2110846119.
  4. Schreiber-Stainthorp W, Solomon J, Lee JH, Castro M, Shah S, Martinez-Orengo N, Reeder R, Maric D, Gross R, Qin J, Hagen KR, Johnson RF, Hammoud DA. Longitudinal in vivo imaging of acute neuropathology in a monkey model of Ebola virus infection. Nat Commun. 2021;12(1):2855.
  5. Anjum S, Dean O, Kosa P, Magone MT, King KA, Fitzgibbon E, Kim HJ, Zalewski C, Murphy E, Billioux BJ, Chisholm J, Brewer CC, Krieger C, Elsegeiny W, Scott TL, Wang J, Hunsberger S, Bennett JE, Nath A, Marr KA, Bielekova B, Wendler D, Hammoud DA, Williamson P. Outcomes in Previously Healthy Cryptococcal Meningoencephalitis Patients Treated With Pulse Taper Corticosteroids for Post-infectious Inflammatory Syndrome. Clin Infect Dis. 2021;73(9):e2789-e2798.

Related Scientific Focus Areas

This page was last updated on Saturday, August 17, 2024