Dima A. Hammoud, M.D.

Senior Investigator

Center for Infectious Disease Imaging (CIDI)

NIH Clinical Center

Building 10, Room 1C368
10 Center Drive
Bethesda, MD 20892



Research Topics

Dr. Hammoud's research interests include the development of preclinical, translational and clinical molecular imaging applications to improve the understanding of the pathophysiology of infection, and to provide reliable imaging biomarkers of infectious diseases. Research in her laboratory focuses on further understanding the pathophysiology of cognitive dysfunction in the setting of HIV infection using non-invasive molecular imaging techniques, mainly positron emission tomography (PET). Current projects include PET imaging of glucose metabolism, neuro-inflammation and neurotransmitter systems in SIV-infected monkeys and HIV infected patients. Another interest of the Hammoud lab is the development and validation of fungal imaging ligands in animal models and patients.


Dr. Hammoud attended college at the American University of Beirut in Lebanon, where she earned a bachelor's degree in biology and an M.D. degree. After completing a residency in diagnostic radiology at the American University of Beirut-Medical Center, she joined the division of neuroradiology at the Johns Hopkins Hospital as a fellow. After completion of her fellowships, she joined the neuroradiology faculty at Johns Hopkins as assistant professor. In 2006, she joined the neuroradiology faculty at NIH. She is currently a tenure track investigator in the Center for Infectious Disease Imaging (CIDI), a joint initiative between Radiology and Imaging Sciences at the NIH Clinical Center and the National Institute of Allergy and Infectious Diseases (NIAID). Dr Hammoud is board-certified in diagnostic imaging by the American Board of Radiology, and has completed fellowships in neuroradiology and PET imaging. She is a member of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) and Radiological Society of North America (RSNA). She currently serves as a member of the Molecular Imaging Abstract Review Subcommittee of the Scientific Program Committee (SPC) and Education Exhibits Committee (EEC) at RSNA and has previously served as a Board member of the Center for Molecular Imaging Innovation and Translation (CMIIT) Program Task Force at SNMMI.

Selected Publications

  1. Shah S, Sinharay S, Matsuda K, Schreiber-Stainthorp W, Muthusamy S, Lee D, Wakim P, Hirsch V, Nath A, Mascio MD, Hammoud DA. Potential Mechanism for HIV-Associated Depression: Upregulation of Serotonin Transporters in SIV-Infected Macaques Detected by 11C-DASB PET. Front Psychiatry. 2019;10:362.

  2. Hammoud DA, Sinharay S, Shah S, Schreiber-Stainthorp W, Maric D, Muthusamy S, Lee DE, Lee CA, Basuli F, Reid WC, Wakim P, Matsuda K, Hirsch V, Nath A, Di Mascio M. Neuroinflammatory Changes in Relation to Cerebrospinal Fluid Viral Load in Simian Immunodeficiency Virus Encephalitis. MBio. 2019;10(3).

  3. Riggle BA, Sinharay S, Schreiber-Stainthorp W, Munasinghe JP, Maric D, Prchalova E, Slusher BS, Powell JD, Miller LH, Pierce SK, Hammoud DA. MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice. Proc Natl Acad Sci U S A. 2018;115(51):E12024-E12033.

  4. Hammoud DA, Boulougoura A, Papadakis GZ, Wang J, Dodd LE, Rupert A, Higgins J, Roby G, Metzger D, Laidlaw E, Mican JM, Pau A, Lage S, Wong CS, Lisco A, Manion M, Sheikh V, Millo C, Sereti I. Increased Metabolic Activity on 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography in Human Immunodeficiency Virus-Associated Immune Reconstitution Inflammatory Syndrome. Clin Infect Dis. 2019;68(2):229-238.

  5. Hammoud DA, Sinharay S, Steinbach S, Wakim PG, Geannopoulos K, Traino K, Dey AK, Tramont E, Rapoport SI, Snow J, Mehta NN, Smith BR, Nath A. Global and regional brain hypometabolism on FDG-PET in treated HIV-infected individuals. Neurology. 2018;91(17):e1591-e1601.

This page was last updated on March 17th, 2020