Daniel S. Chertow, M.D., M.P.H.

Senior Investigator

Emerging Pathogens Section

NIH Clinical Center

Building 10, Room 2C145
10 Center Drive
Bethesda, MD 20892

301-496-9320

chertowd@cc.nih.gov

Research Topics

Influenza pathogenesis and treatment are research interests of Dr. Chertow. Recent investigations have focused on the study of influenza and bacterial co-pathogenesis in a mouse model and characterization of the clinical, microbiologic, and molecular virology features of fatal 1918 influenza and pneumonia cases.

Biography

Dr. Chertow is a Tenure-Track Investigator in the Critical Care Medicine Department at the National Institutes of Health (NIH) Clinical Center and in the Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases. He is a Fellow in the American College of Critical Care Medicine, and a member of the Infectious Diseases Society of America and the American Public Health Association. He serves as a senior officer in the United States Public Health Service (USPHS).

Dr. Chertow received his undergraduate degree in Sociology from Boston College, his degree in Medicine from Northwestern University, and his degree in Public Health from the University of California, Berkeley. He completed residency training in Internal Medicine at the University of California, San Diego and training as an Epidemic Intelligence Service Officer at the United States Centers for Disease Control and Prevention. Fellowship training in Critical Care Medicine was completed at NIH and Infectious Diseases at Johns Hopkins University.

Dr. Chertow's translational research program employs advanced animal models and detailed natural history studies in humans to improve understanding of the pathophysiology and molecular pathogenesis of severe emerging viral infections including Influenza A, Ebola, and Zika viruses to guide improved clinical management of these infections.

Honors and Awards
USPHS Meritorious Service Medal, 2017; USPHS Presidential Unit Citation, 2016; Lasker-Bloomberg Public Service Award, 2015; NIH Director's Award, 2015; NIH Clinical Center Director's Award, 2014; USPHS Unit Commendations, 2012, 2010, and 2005; USPHS Citation, 2011

Selected Publications

  1. Chertow DS, Kleine C, Edwards JK, Scaini R, Giuliani R, Sprecher A. Ebola virus disease in West Africa--clinical manifestations and management. N Engl J Med. 2014;371(22):2054-7.
  2. Chertow DS, Nath A, Suffredini AF, Danner RL, Reich DS, Bishop RJ, Childs RW, Arai AE, Palmore TN, Lane HC, Fauci AS, Davey RT. Severe Meningoencephalitis in a Case of Ebola Virus Disease: A Case Report. Ann Intern Med. 2016;165(4):301-4.
  3. Barnes KG, Kindrachuk J, Lin AE, Wohl S, Qu J, Tostenson SD, Dorman WR, Busby M, Siddle KJ, Luo CY, Matranga CB, Davey RT, Sabeti PC, Chertow DS. Evidence of Ebola Virus Replication and High Concentration in Semen of a Patient During Recovery. Clin Infect Dis. 2017;65(8):1400-1403.
  4. Khurana S, Ravichandran S, Hahn M, Coyle EM, Stonier SW, Zak SE, Kindrachuk J, Davey RT Jr, Dye JM, Chertow DS. Longitudinal Human Antibody Repertoire against Complete Viral Proteome from Ebola Virus Survivor Reveals Protective Sites for Vaccine Design. Cell Host Microbe. 2020;27(2):262-276.e4.
  5. Stein SR, Ramelli SC, Grazioli A, Chung JY, Singh M, Yinda CK, Winkler CW, Sun J, Dickey JM, Ylaya K, Ko SH, Platt AP, Burbelo PD, Quezado M, Pittaluga S, Purcell M, Munster VJ, Belinky F, Ramos-Benitez MJ, Boritz EA, Lach IA, Herr DL, Rabin J, Saharia KK, Madathil RJ, Tabatabai A, Soherwardi S, McCurdy MT, NIH COVID-19 Autopsy Consortium, Peterson KE, Cohen JI, de Wit E, Vannella KM, Hewitt SM, Kleiner DE, Chertow DS. SARS-CoV-2 infection and persistence in the human body and brain at autopsy. Nature. 2022;612(7941):758-763.

Related Scientific Focus Areas

This page was last updated on Saturday, September 2, 2023