Chuong Dinh Hoang, M.D.

Investigator

Thoracic and Gastrointestinal Oncology Branch

NCI/CCR

Building 10-CRC, Room 4-3950
Bethesda, MD 20892

3014962126

chuong.hoang@nih.gov

Research Topics

My research interests are in developing novel biomarkers and therapeutic strategies in malignant mesothelioma by systematically identifying and exploiting disease-specific microRNA.  Some of these concepts can also be applied to thymic tumors, a second major area of focus.

Biography

Dr. Hoang received his medical degree from the University of Minnesota Medical School, where he stayed to complete clinical training in general surgery.  During his surgical residency his research work was supported by the Ruth L. Kirschstein National Research Service Award and a Training Program Grant in the Division of Hematology-Oncology.  Afterwards, Dr. Hoang completed his cardiothoracic residency at the University of Pennsylvania, with an emphasis on thoracic surgery. Since 2008, he then served on faculty at Stanford University School of Medicine as an Assistant Professor.  He was the Medical (co-)Director of the Stanford Cancer Center Tissue Bank.  Dr. Hoang also established an independent thoracic oncology laboratory there investigating the metabolic derangements in lung cancer and microRNA interactions in mesothelioma.

Selected Publications

  1. Xu Y, Zheng M, Merritt RE, Shrager JB, Wakelee HA, Kratzke RA, Hoang CD. miR-1 induces growth arrest and apoptosis in malignant mesothelioma. Chest. 2013;144(5):1632-1643.

  2. Zheng Y, de la Cruz CC, Sayles LC, Alleyne-Chin C, Vaka D, Knaak TD, Bigos M, Xu Y, Hoang CD, Shrager JB, Fehling HJ, French D, Forrest W, Jiang Z, Carano RA, Barck KH, Jackson EL, Sweet-Cordero EA. A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal. Cancer Cell. 2013;24(1):59-74.

  3. Chen R, Khatri P, Mazur PK, Polin M, Zheng Y, Vaka D, Hoang CD, Shrager J, Xu Y, Vicent S, Butte AJ, Sweet-Cordero EA. A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma. Cancer Res. 2014;74(10):2892-902.

  4. Newman AM, Liu CL, Green MR, Gentles AJ, Feng W, Xu Y, Hoang CD, Diehn M, Alizadeh AA. Robust enumeration of cell subsets from tissue expression profiles. Nat Methods. 2015;12(5):453-7.


This page was last updated on June 15th, 2017