Catherine Weisz, Ph.D.
Section on Neuronal Circuitry
Porter Neuroscience Research Center, Room 3E-4503
35A Convent Drive
Bethesda, MD 20892
The laboratory of neuronal circuitry (1) investigates the communication between neurons of the auditory system; (2) employs electrophysiology and optical techniques in in vitro preparations to study synaptic transmission between neurons; (3) integrates knowledge of neuronal synaptic inputs with electrical properties to determine the functional properties of neurons of the auditory system; (4) extends knowledge gained from in vitro brain and cochlea preparations to animal models including models of acoustic trauma; and (5) seeks to understand how the interplay between auditory neuronal pathways shapes acoustic perception in both the normal and damaged auditory system.
Dr. Weisz received a B.S. degree in neurobiology from Cornell University, a M.S. in biotechnology from Johns Hopkins University, and a Ph.D. in neuroscience from Johns Hopkins University School of Medicine. Her graduate work involved studies of synaptic inputs and electrical properties of cochlear type II spiral ganglion afferent neurons in the laboratories of Dr. Paul Fuchs and Dr. Elisabeth Glowatzki. Post-doctoral work in the laboratory of Dr. Karl Kandler at the University of Pittsburgh School of Medicine investigated the development of circuits between brainstem neurons involved in sound localization. In 2015, Dr. Weisz moved to the NIDCD, where she became Acting Chief of the Section on Neuronal Circuitry. Dr. Weisz’s laboratory investigates the synaptic transmission and electrical properties of descending neuronal circuitry in the auditory brainstem and cochlea.
Kitcher SR, Weisz CJ. Shedding light on optical cochlear implant progress. EMBO Mol Med. 2020;12(8):e12620.
Torres Cadenas L, Fischl MJ, Weisz CJC. Synaptic Inhibition of Medial Olivocochlear Efferent Neurons by Neurons of the Medial Nucleus of the Trapezoid Body. J Neurosci. 2020;40(3):509-525.
Martinez-Monedero R, Liu C, Weisz C, Vyas P, Fuchs PA, Glowatzki E. GluA2-Containing AMPA Receptors Distinguish Ribbon-Associated from Ribbonless Afferent Contacts on Rat Cochlear Hair Cells. eNeuro. 2016;3(2).
Weisz CJ, Rubio ME, Givens RS, Kandler K. Excitation by Axon Terminal GABA Spillover in a Sound Localization Circuit. J Neurosci. 2016;36(3):911-25.
Sturm JJ, Weisz CJ. Hyperactivity in the medial olivocochlear efferent system is a common feature of tinnitus and hyperacusis in humans. J Neurophysiol. 2015;114(5):2551-4.
Related Scientific Focus Areas
Biomedical Engineering and Biophysics
This page was last updated on August 13th, 2020